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Found 3 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM443430'
TargetEstrogen receptor(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM443430(US10654866, Example 1B | US11117902, Example 1A | ...)
Affinity DataKi:  0.310nMAssay Description:Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM443430(US10654866, Example 1B | US11117902, Example 1A | ...)
Affinity DataKi:  0.310nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM443430(US10654866, Example 1B | US11117902, Example 1A | ...)
Affinity DataKi:  12.4nMAssay Description:The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...More data for this Ligand-Target Pair
In DepthDetails US Patent