Found 6 Enz. Inhib. hit(s) with Target = 'GTPase KRas' and Ligand = 'BDBM50514402' 
Affinity DataKi: 1.22E+4nMAssay Description:Binding affinity to KRAS G12C mutant (unknown origin) assessed as inhibition constant incubated for 24 hrs by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 8.60E+4nMAssay Description:Binding affinity to KRAS (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataIC50: 9.70nMAssay Description:Inhibition of KRAS G12C mutant (unknown origin) assessed as inhibition of SOS1-catalyzed nucleotide exchange measured by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as reduction in p-ERK levelsMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Inhibition of KRAS in human MIAPaca2 cells assessed as decrease in EGF-stimulated ERK1/2 phosphorylation preincubated for 2 hrs followed by EGF stimu...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KRAS (2 to 185 residues) expressed in baculovirus infected Sf9 insect cells using GTP as substr...More data for this Ligand-Target Pair
