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Found 8 Enz. Inhib. hit(s) with Target = 'Hexokinase-4' and Ligand = 'BDBM50239046'
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239046(CHEMBL4068048)
Affinity DataEC50:  31nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239046(CHEMBL4068048)
Affinity DataEC50:  3.90nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239046(CHEMBL4068048)
Affinity DataEC50:  3.90nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239046(CHEMBL4068048)
Affinity DataEC50:  5.20nMAssay Description:Activation of glucokinase in primary rat hepatocytes assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239046(CHEMBL4068048)
Affinity DataEC50:  9.80nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239046(CHEMBL4068048)
Affinity DataEC50:  9.80nMAssay Description:Inhibition of cGMP PDE II enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239046(CHEMBL4068048)
Affinity DataEC50:  31nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239046(CHEMBL4068048)
Affinity DataEC50:  5.20nMAssay Description:Activation of glucokinase in primary rat hepatocytes assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed