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Found 5 Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50058914'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058914(CHEMBL303597 | [6-(4-Carbamimidoyl-benzoylamino)-1...)
Affinity DataIC50:  3nMAssay Description:Inhibition of fibrinogen binding to purified human alpha IIb beta3 integrin (GP IIb-IIIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058914(CHEMBL303597 | [6-(4-Carbamimidoyl-benzoylamino)-1...)
Affinity DataIC50:  3nMAssay Description:Inhibition of fibrinogen binding to purified Human alphaIIb-beta3 integrin in ELISA with 1% bovine serum albumin (BSA)More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058914(CHEMBL303597 | [6-(4-Carbamimidoyl-benzoylamino)-1...)
Affinity DataIC50:  76nMAssay Description:Concentration required to reduce binding of fibrinogen to purified Fibrinogen Receptor by 50% using ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058914(CHEMBL303597 | [6-(4-Carbamimidoyl-benzoylamino)-1...)
Affinity DataIC50:  90nMAssay Description:Inhibition of ADP induced platelet aggregation in human platelet-rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50058914(CHEMBL303597 | [6-(4-Carbamimidoyl-benzoylamino)-1...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibition of gel filtered platelet aggregation induced by ADP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed