Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM50503631'
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50503631(CHEMBL4436792)
Affinity DataIC50:  280nMAssay Description:Inhibition of human LSD1 (unknown orgin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50503631(CHEMBL4436792)
Affinity DataIC50:  283nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Hamster isolated trachea(HT) assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50503631(CHEMBL4436792)
Affinity DataIC50:  283nMAssay Description:Inhibition of full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 peptide as substrate after 30 mins by fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50503631(CHEMBL4436792)
Affinity DataIC50:  283nMAssay Description:Inhibition of recombinant LSD1 (157 to 852 residues) (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 as substrate by amplex re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50503631(CHEMBL4436792)
Affinity DataKd:  1nMAssay Description:Binding affinity to full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) assessed as dissociation rate constant by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50503631(CHEMBL4436792)
Affinity DataKd:  5.5nMAssay Description:Binding affinity to full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed