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Found 2 Enz. Inhib. hit(s) with Target = 'Lysosomal acid glucosylceramidase' and Ligand = 'BDBM18362'
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18362((2R,3S,4R,5R,6R)-2-hexyl-6-(hydroxymethyl)piperidi...)
Affinity DataKi:  2.30E+3nM ΔG°:  -33.5kJ/mole IC50:  4.20E+3nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18362((2R,3S,4R,5R,6R)-2-hexyl-6-(hydroxymethyl)piperidi...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human recombinant beta-glucocerebrosidase preincubated for 10 mins before 4-methylumbelliferyl-betaD-glucopyranoside addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed