Found 5 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 11/12/13/14' and Ligand = 'BDBM50130648' TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibitory activity against induction of IL-1-beta release in PBMCsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 at 10 e-4 to 10 e-8 M concentrationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against TNF-alpha release in PBM cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of p38-related IL1-beta release by whole blood cells at 10 e-4 to 10 e-8 MMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Eberhard-Karls-University T£Bingen
Curated by ChEMBL
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of p38-related TNF-alpha release by whole blood cells at 10 e-4 to 10 e-8 MMore data for this Ligand-Target Pair
