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Found 3 Enz. Inhib. hit(s) with Target = 'Mixed lineage kinase domain-like protein' and Ligand = 'BDBM534351'
TargetMixed lineage kinase domain-like protein(Homo sapiens)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534351(WO2018148626, Example 78 | WO2022086828, Example 7...)
Affinity DataIC50:  9.90nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMixed lineage kinase domain-like protein(Homo sapiens)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534351(WO2018148626, Example 78 | WO2022086828, Example 7...)
Affinity DataIC50:  19nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMixed lineage kinase domain-like protein(Homo sapiens)
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534351(WO2018148626, Example 78 | WO2022086828, Example 7...)
Affinity DataIC50:  146nMAssay Description:HT29-L23 human colorectal adenocarcinoma cells were maintained in RPMI 1640 medium containing 10% heat-inactivated FBS, 1% Penicillin-Streptomycin an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed