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Found 1 Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2' and Ligand = 'BDBM633269'
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM633269(US20190276450, Example 1b.5)
Affinity DataEC50:  18nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent