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Found 1 Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM307569'
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM307569(1-(2-((2R,4R)-4-((4-(2,2- difluoroethoxy)pyridin-2...)
Affinity DataIC50:  65.1nMAssay Description: All reagents were from GIBCO-Invitrogen Corp. The seeded plates are incubated overnight at 37° C. and 5% CO2. Ala-6,12 human orexin-A as the agonist...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent