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Found 2 Enz. Inhib. hit(s) with Target = 'Poly(ADP-ribose) glycohydrolase' and Ligand = 'BDBM616694'
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
280 Bio

US Patent
LigandPNGBDBM616694(US20230278998, Comparative Compound 1' | US2023030...)
Affinity DataIC50:  1.90nMAssay Description:PARG in vitro assays were conducted in standard 384-well plates in a total volume of 15 μL. 5 μL of PARG (389-976) (manufactured by Chempar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
280 Bio

US Patent
LigandPNGBDBM616694(US20230278998, Comparative Compound 1' | US2023030...)
Affinity DataEC50:  19nMAssay Description:PARG enzyme was incubated with compound or vehicle (DMSO) and the biotinylated-PARylated PARP-1 substrate in a microtiter plate. After adding detecti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent