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Found 3 Enz. Inhib. hit(s) with Target = 'Potassium channel subfamily K member 3' and Ligand = 'BDBM458966'
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM458966((4-{[2-(4-Bromophenyl)imidazo [1,2-a]pyridin-3-yl]...)
Affinity DataIC50:  9.70nMAssay Description:The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM458966((4-{[2-(4-Bromophenyl)imidazo [1,2-a]pyridin-3-yl]...)
Affinity DataIC50:  172nMAssay Description:The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM458966((4-{[2-(4-Bromophenyl)imidazo [1,2-a]pyridin-3-yl]...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of human TASK-1 expressed in Xenopus laevis oocytes assessed as inhibition of channel current at +40mV holding potential by two-electrode ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB