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Found 4 Enz. Inhib. hit(s) with Target = 'Proprotein convertase subtilisin/kexin type 9' and Ligand = 'BDBM50275436'
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))TBA
LigandPNGBDBM50275436(CHEMBL4128250)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human C-terminal V5 epitope tagged PCSK9 by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))TBA
LigandPNGBDBM50275436(CHEMBL4128250)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human recombinant full length ProLabel-tagged PCSK9 expressed in CHO-K1 cells incubated overnight and measured after 3 days by HTS assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))TBA
LigandPNGBDBM50275436(CHEMBL4128250)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant PCSK9 expressed in CHO-K1 cells assessed as alkaline phosphatase secretion incubated overnight and measured after 3 d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))TBA
LigandPNGBDBM50275436(CHEMBL4128250)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human recombinant full length ProLabel-tagged PCSK9 expressed in CHO-K1 cells incubated overnight and measured after 3 days by chemilum...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed