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Found 2 Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-10' and Ligand = 'BDBM50277889'
TargetProteasome subunit beta type-10(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50277889(CARFILZOMIB | CHEMBL451887)
Affinity DataIC50:  13nMAssay Description:Inhibition of human 20S immunoproteasome beta-2i subunit using Ac-RLR-AMC as substrate preincubated for 2 hrs followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetProteasome subunit beta type-10(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50277889(CARFILZOMIB | CHEMBL451887)
Affinity DataIC50:  620nMAssay Description:Inhibition of 20S proteasome beta 2i (unknown origin) after 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank