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Found 4 Enz. Inhib. hit(s) with Target = 'Regulator of G-protein signaling 17' and Ligand = 'BDBM25525'
TargetRegulator of G-protein signaling 17(Homo sapiens)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM25525(24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of RGS17 (unknown origin) GAP activity in presence of GTP by malachite green dye based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRegulator of G-protein signaling 17(Homo sapiens)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM25525(24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11...)
Affinity DataIC50:  7.28E+4nMAssay Description:Inhibition of wild type GST-tagged RGS17 (unknown origin) interaction with biotinylated Galphao after 30 mins in presence of AMF and GDP by AlphaScre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRegulator of G-protein signaling 17(Homo sapiens)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM25525(24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of RGS17 (unknown origin) C117A mutant interaction with biotinylated Galphao after 30 mins in presence of AMF and GDP by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRegulator of G-protein signaling 17(Homo sapiens)
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM25525(24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11...)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to RGS17 (unknown origin) by ITC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed