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Found 3 Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1' and Ligand = 'BDBM412127'
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM412127(US10392402, Compound ID 5 | US10807966, Compound 2...)
Affinity DataIC50:  73nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM412127(US10392402, Compound ID 5 | US10807966, Compound 2...)
Affinity DataIC50:  73nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Translational Drug Development

US Patent
LigandPNGBDBM412127(US10392402, Compound ID 5 | US10807966, Compound 2...)
Affinity DataIC50:  130nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent