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Found 3 Enz. Inhib. hit(s) with Target = 'Short transient receptor potential channel 4' and Ligand = 'BDBM77617'
TargetShort transient receptor potential channel 4(Mus musculus)
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM77617(4-methyl-2-(1-piperidinyl)quinoline | 4-methyl-2-p...)
Affinity DataIC50:  960nMAssay Description:Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced intracellular calciu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 4(Mus musculus)
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM77617(4-methyl-2-(1-piperidinyl)quinoline | 4-methyl-2-p...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced current by QPatch cl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 4(Mus musculus)
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM77617(4-methyl-2-(1-piperidinyl)quinoline | 4-methyl-2-p...)
Affinity DataIC50:  2.63E+3nMAssay Description:Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay