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Found 3 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50175157'
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50175157(CHEMBL371932 | N-(bis(4-fluorophenyl)methyl)-8-but...)
Affinity DataKi:  21.5nMAssay Description:Displacement of [3H]WIN-from DAT in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50175157(CHEMBL371932 | N-(bis(4-fluorophenyl)methyl)-8-but...)
Affinity DataKi:  24nMAssay Description:Inhibition of [3H]WIN5428 uptake at wild type human DAT expressed in African green monkey COS7 cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50175157(CHEMBL371932 | N-(bis(4-fluorophenyl)methyl)-8-but...)
Affinity DataKi:  62nMAssay Description:Inhibition of [3H]DA uptake at wild type human DAT expressed in African green monkey COS7 cells after 5 mins by beta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed