Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with Target = 'Sphingosine kinase 1' and Ligand = 'BDBM50438143'
TargetSphingosine kinase 1(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50438143(CHEMBL2409891)
Affinity DataIC50:  10nMAssay Description:Inhibition of human SphK1 using sphingosine as substrate incubated for 50 mins by scintillation counting analysis in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50438143(CHEMBL2409891)
Affinity DataIC50:  20nMAssay Description:Inhibition of purified human SphK1 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50438143(CHEMBL2409891)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant SphK1 expressed in Sf9 cells assessed as radiolabeled products using 5 uM sphingosine and 10 uM gamma[32P]ATP by liqu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50438143(CHEMBL2409891)
Affinity DataIC50:  70nMAssay Description:Inhibition of mouse SphK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50438143(CHEMBL2409891)
Affinity DataEC50:  90nMAssay Description:Inhibition of SphK1 in human WM266-4 cells assessed as inhibition of formation of [17C]-S1P formation after 20 mins by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed