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Found 2 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 8' and Ligand = 'BDBM50586260'
TargetToll-like receptor 8(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50586260(CHEMBL5079910)
Affinity DataIC50:  0.200nMAssay Description:Antagonist activity at human TLR8 expressed in human PBMC cells assessed as inhibition of ssRNA stimulated TNF level preincubated for 30 mins followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 8(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50586260(CHEMBL5079910)
Affinity DataIC50:  2.40nMAssay Description:Antagonist activity at human TLR8 expressed in Drosophila S2 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed