Affinity DataIC50: 0.0360nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataIC50: 0.0470nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataIC50: 0.450nMAssay Description:In vitro inhibitory activity in human whole blood (HWB) elastase at a concentration of 10More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [3H]-dexamethasone binding to human Glucocorticoid ReceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.690nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Binding affinity for dopamine D4-like receptor labelled with [3H]YM-09151-2 in retinaMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:In vitro inhibitory activity in human whole blood (HWB) elastase at a concentration of 10 uMMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxo Group Research
Curated by ChEMBL
Glaxo Group Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of [3H]-dexamethasone binding to human Glucocorticoid ReceptorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of [3H]-dexamethasone binding to human Glucocorticoid ReceptorMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxo Group Research
Curated by ChEMBL
Glaxo Group Research
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibitory activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxo Group Research
Curated by ChEMBL
Glaxo Group Research
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxo Group Research
Curated by ChEMBL
Glaxo Group Research
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Inhibitory activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxo Group Research
Curated by ChEMBL
Glaxo Group Research
Curated by ChEMBL
Affinity DataIC50: 9.90nMAssay Description:Inhibitory activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:In vitro inhibitory activity in human whole blood (HWB) elastaseMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against ElastaseMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:The compound was evaluated for its inhibitory activity against Chymotrypsinogen using selectivity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:The compound was evaluated for its inhibitory activity against dog neutrophil elastase using whole blood assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibitory concentration against ElastaseMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre
Curated by ChEMBL
Gsk Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre
Curated by ChEMBL
Gsk Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre
Curated by ChEMBL
Gsk Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of TXK (unknown origin)More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Harvard School of Public Health
Harvard School of Public Health
Affinity DataIC50: 80nMAssay Description:Substrate-dependent inhibition of recombinant PfDHODH protein was assessed in an in vitro assay in 384-well clear plates (Corning 3702) as described ...More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre
Curated by ChEMBL
Gsk Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
Affinity DataIC50: 94nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration against ElastaseMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:In vitro inhibitory activity in human whole blood (HWB) elastase at a concentration of 10 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE) using whole blood assayMore data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Inhibition of IR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Inhibition of Bmx (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:The compound was evaluated for its inhibitory activity against dog neutrophil elastase using whole blood assayMore data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Gsk Medicines Research Centre
Curated by ChEMBL
Gsk Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 181nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE) using whole blood assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataIC50: 194nMAssay Description:Inhibition of [3H]-dexamethasone binding to human Glucocorticoid ReceptorMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of CAMKK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 242nMAssay Description:Inhibitory concentration against ElastaseMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE) using whole blood assayMore data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Inhibition of Tec (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:The compound was evaluated for its inhibitory activity against dog neutrophil elastase using whole blood assayMore data for this Ligand-Target Pair
Affinity DataIC50: 274nMAssay Description:Inhibitory concentration against ElastaseMore data for this Ligand-Target Pair