Compile Data Set for Download or QSAR
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Found 823 of ic50 for UniProtKB: P33535
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50190307(Ac-RYYRIK-GGG-K-(NH2)-YAFGYPS-GG | CHEMBL414736)
Affinity DataIC50:  0.00236nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232770((S)-2-Amino-N-{[(S)-1-((R)-1-carbamoyl-2-naphthale...)
Affinity DataIC50:  0.0100nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594844(CHEMBL5199190)
Affinity DataIC50:  0.0200nMAssay Description:Inhibition of Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50037079(CHEMBL3355781)
Affinity DataIC50:  0.0220nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50278897((R)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50:  0.0350nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594842(CHEMBL5199205)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50037080(CHEMBL3355780)
Affinity DataIC50:  0.0400nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50278895((R)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50:  0.0400nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50001852(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-1-{2-[(3...)
Affinity DataIC50:  0.0450nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50190308(Ac-RYYRIK-GGG-K-(NH2)-YRFB-GGGGG | CHEMBL441930)
Affinity DataIC50:  0.0477nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594843(CHEMBL5175678)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50453625(CHEMBL2110229)
Affinity DataIC50:  0.100nMAssay Description:Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50318416(7alpha-(1-Hydroxy-1-methyl-ethyl)-6-phenyl-6-demet...)
Affinity DataIC50:  0.110nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50001850((S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(...)
Affinity DataIC50:  0.130nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50001848(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[1-met...)
Affinity DataIC50:  0.130nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50318412(7alpha-(1-Hydroxy-1-methyl-ethyl)-6-propoxy-6-deme...)
Affinity DataIC50:  0.130nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50036787(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...)
Affinity DataIC50:  0.130nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50036787(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...)
Affinity DataIC50:  0.130nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of [3H]DAMGO radioligand binding to rat brain opioid receptor mu 1.More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50318415(7alpha-(1-Hydroxy-1-methyl-ethyl)-6-(cyclopropylme...)
Affinity DataIC50:  0.140nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50367123(ETORPHINE | M99)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of [3H]- DAMGO binding to Rat brain Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of [3H]DAMGO radioligand binding to rat brain opioid receptor mu 1.More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50190306(Ac-RYYRIK-K-(NH2)-YAFGYPS | CHEMBL404792)
Affinity DataIC50:  0.150nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50318413(7alpha-(1-Hydroxy-1-methyl-ethyl)-6-ethoxy-6-demet...)
Affinity DataIC50:  0.180nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50453625(CHEMBL2110229)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50176702((S)-2-amino-N-{(4S,10S,15S,21S)-21-[(S)-2-amino-3-...)
Affinity DataIC50:  0.200nMAssay Description:Agonistic efficacy at rat mu opioid receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50450653(CHEMBL2115493)
Affinity DataIC50:  0.25nMAssay Description:Binding affinity against rat mu-opioid receptor expressed in CHO cells by competitive inhibition of 1 nM [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50359547(CHEMBL1927271)
Affinity DataIC50:  0.260nMAssay Description:Displacement of [3H]DAMGO from Wistar rat mu opioid receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594838(CHEMBL5171420)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50500609(CHEMBL3754056)
Affinity DataIC50:  0.275nMAssay Description:Displacement of [3H]DAMGO from mu-opioid receptor in Sprague-Dawley rat brain membrane after 180 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50122099(CHEMBL3617471)
Affinity DataIC50:  0.275nMAssay Description:Displacement of [3H] DAMGO from rat mu-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50393258(CHEMBL2151734)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [3H]naloxone from MOR in rat brain homogenates by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50334993((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-((R...)
Affinity DataIC50:  0.339nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50278893((R)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50:  0.380nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50334996((S)-2-amino-N-((R)-1-(2-((S)-3-(4-chlorophenyl)-1-...)
Affinity DataIC50:  0.389nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50092198(CHEMBL3580743)
Affinity DataIC50:  0.420nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095155((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataIC50:  0.430nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50096787(CHEMBL3580749)
Affinity DataIC50:  0.490nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095155((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of [3H]DAMGO binding to Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50001846(2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[1-met...)
Affinity DataIC50:  0.5nMAssay Description:Binding ability towards opioid receptor mu expressed in homogenates of rat brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50188149(4-[(2S)-2-(dimethylamino)-3-{[(2S)-1-(4-hydroxyphe...)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50280346((S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyla...)
Affinity DataIC50:  0.5nMAssay Description:Compound was evaluated for its binding affinity against enkephalin mu receptor using [3H]-PL-017 as ligand in rat cerebrum in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095155((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataIC50:  0.5nMAssay Description:Inhibitory activity against [3H]DAMGO binding to Opioid receptor mu 1 in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50059841((S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataIC50:  0.538nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50318414(7alpha-(1-Hydroxy-1-methyl-ethyl)-6,7,8,14-tetrahy...)
Affinity DataIC50:  0.540nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50096744(CHEMBL3580746)
Affinity DataIC50:  0.540nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50096745(CHEMBL3580745)
Affinity DataIC50:  0.550nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataIC50:  0.560nMAssay Description:Displacement of [3H]DAMGO from Wistar rat mu opioid receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataIC50:  0.560nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
In DepthDetails PubMed
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