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TargetD-amino-acid oxidase(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50433372(CHEMBL2375520)
Affinity DataKi:  1.70nMAssay Description:Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50260725(4H-thieno[3,2-b]pyrrole-5-carboxylic acid | CHEMBL...)
Affinity DataKi:  3.5nMAssay Description:Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD-amino-acid oxidase(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50260722(4-(4-chlorophenethyl)-1H-pyrrole-2-carboxylic acid...)
Affinity DataKi:  7.20nMAssay Description:Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD-amino-acid oxidase(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50206007(3-hydroxy-2H-chromen-2-one | 3-Hydroxy-chromen-2-o...)
Affinity DataKi:  13nMAssay Description:Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD-amino-acid oxidase(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM31147(4H-furo[3,2-b]pyrrole-5-carboxylic acid | CHEMBL49...)
Affinity DataKi:  36nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DAO expressed in Escherichia coli BL21(DE3) using D-serine as substrate by Lineweaver-Burk plot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50117763(US9505753, 5u | CHEMBL3613921)
Affinity DataKi:  60nMAssay Description:Competitive inhibition of recombinant human DAAO expressed in HEK cells by double reciprocal plot analysis in presence of D-serineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50206007(3-hydroxy-2H-chromen-2-one | 3-Hydroxy-chromen-2-o...)
Affinity DataKi:  156nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DAO expressed in Escherichia coli BL21(DE3) using D-serine as substrate by Lineweaver-Burk plot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD-amino-acid oxidase(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50433371(CHEMBL2375519)
Affinity DataKi:  190nMAssay Description:Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM36181(benzoic acid | benzoate | SODIUM BENZOATE | benzoi...)
Affinity DataKi:  2.00E+3nMAssay Description:Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM36181(benzoic acid | benzoate | SODIUM BENZOATE | benzoi...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of human recombinant DAO expressed in Escherichia coli BL21(DE3) by oxygraphic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50074328(Thiophene-3-carboxylic acid | CHEMBL164585)
Affinity DataKi:  8.16E+3nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DAO expressed in Escherichia coli BL21(DE3) using D-serine as substrate by Lineweaver-Burk plot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50427206(CHEMBL2324852)
Affinity DataKi:  9.92E+3nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DAO expressed in Escherichia coli BL21(DE3) using D-serine as substrate by Lineweaver-Burk plot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM36181(benzoic acid | benzoate | SODIUM BENZOATE | benzoi...)
Affinity DataKi:  1.09E+4nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DAO expressed in Escherichia coli BL21(DE3) using D-serine as substrate by Lineweaver-Burk plot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50158869(CHEMBL3786182 | US10836743, Compound GSK-2879552 |...)
Affinity DataKi:  5.20E+5nMAssay Description:Binding affinity to D-amino acid oxidase (unknown origin) assessed as apparent inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details