Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 2313
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

LigandPNGBDBM19235(2-{5-[4-({[(2,4-difluorophenyl)methyl](3-methanesu...)
Affinity DataIC50:  0.200nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19234(4-{4-[3-(4-{[benzyl(3-methanesulfonamido-2-methylp...)
Affinity DataIC50:  0.600nM EC50:  86nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the 3(H)-dexamethasone from the receptor an IC50 value (the concentration required to inhibit 50% of the binding of 3(...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

LigandPNGBDBM19234(4-{4-[3-(4-{[benzyl(3-methanesulfonamido-2-methylp...)
Affinity DataIC50:  1nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  1.10nM EC50:  4.80nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the 3(H)-dexamethasone from the receptor an IC50 value (the concentration required to inhibit 50% of the binding of 3(...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  1.40nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19236(2-{2-bromo-5-[4-({[(2,4-difluorophenyl)methyl](3-m...)
Affinity DataIC50:  1.80nM EC50:  330nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the 3(H)-dexamethasone from the receptor an IC50 value (the concentration required to inhibit 50% of the binding of 3(...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

LigandPNGBDBM19238(2-{2-chloro-5-[4-({[(2,4-difluorophenyl)methyl](3-...)
Affinity DataIC50:  1.90nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

LigandPNGBDBM19237(2-[4-(4-{[benzyl(3-methanesulfonamido-2-methylphen...)
Affinity DataIC50:  2.10nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Abbott Laboratories

LigandPNGBDBM19233((2R,10S,11S,14S,15S)-14-hydroxy-15-methyl-2-[(4-me...)
Affinity DataIC50:  2.40nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19233((2R,10S,11S,14S,15S)-14-hydroxy-15-methyl-2-[(4-me...)
Affinity DataIC50:  2.40nM EC50:  43nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the 3(H)-dexamethasone from the receptor an IC50 value (the concentration required to inhibit 50% of the binding of 3(...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19238(2-{2-chloro-5-[4-({[(2,4-difluorophenyl)methyl](3-...)
Affinity DataIC50:  2.60nM EC50:  500nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the 3(H)-dexamethasone from the receptor an IC50 value (the concentration required to inhibit 50% of the binding of 3(...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  2.90nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19235(2-{5-[4-({[(2,4-difluorophenyl)methyl](3-methanesu...)
Affinity DataIC50:  4.80nM EC50:  440nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the 3(H)-dexamethasone from the receptor an IC50 value (the concentration required to inhibit 50% of the binding of 3(...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19237(2-[4-(4-{[benzyl(3-methanesulfonamido-2-methylphen...)
Affinity DataIC50:  5.40nM EC50:  255nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the 3(H)-dexamethasone from the receptor an IC50 value (the concentration required to inhibit 50% of the binding of 3(...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  8.80nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19234(4-{4-[3-(4-{[benzyl(3-methanesulfonamido-2-methylp...)
Affinity DataIC50:  120nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19236(2-{2-bromo-5-[4-({[(2,4-difluorophenyl)methyl](3-m...)
Affinity DataIC50:  140nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19238(2-{2-chloro-5-[4-({[(2,4-difluorophenyl)methyl](3-...)
Affinity DataIC50:  150nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19235(2-{5-[4-({[(2,4-difluorophenyl)methyl](3-methanesu...)
Affinity DataIC50:  180nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19234(4-{4-[3-(4-{[benzyl(3-methanesulfonamido-2-methylp...)
Affinity DataIC50:  550nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19237(2-[4-(4-{[benzyl(3-methanesulfonamido-2-methylphen...)
Affinity DataIC50:  690nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19238(2-{2-chloro-5-[4-({[(2,4-difluorophenyl)methyl](3-...)
Affinity DataIC50:  1.00E+3nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19234(4-{4-[3-(4-{[benzyl(3-methanesulfonamido-2-methylp...)
Affinity DataIC50:  1.60E+3nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19237(2-[4-(4-{[benzyl(3-methanesulfonamido-2-methylphen...)
Affinity DataIC50:  1.70E+3nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19233((2R,10S,11S,14S,15S)-14-hydroxy-15-methyl-2-[(4-me...)
Affinity DataIC50:  2.40E+3nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19238(2-{2-chloro-5-[4-({[(2,4-difluorophenyl)methyl](3-...)
Affinity DataIC50:  3.60E+3nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  6.00E+3nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19233((2R,10S,11S,14S,15S)-14-hydroxy-15-methyl-2-[(4-me...)
Affinity DataIC50:  6.30E+3nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19233((2R,10S,11S,14S,15S)-14-hydroxy-15-methyl-2-[(4-me...)
Affinity DataIC50:  6.50E+3nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19237(2-[4-(4-{[benzyl(3-methanesulfonamido-2-methylphen...)
Affinity DataIC50:  1.17E+4nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed