Affinity DataIC50: 5nMAssay Description:In vitro inhibitory concentration against angiotensin-converting enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...More data for this Ligand-Target Pair
TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2 [K89T](Homo sapiens (Human))
University Of Oxford
University Of Oxford
Affinity DataIC50: 8.90nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...More data for this Ligand-Target Pair
TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2 [L83V,H84D](Homo sapiens (Human))
University Of Oxford
University Of Oxford
Affinity DataIC50: 21nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...More data for this Ligand-Target Pair
TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2 [F82H](Homo sapiens (Human))
University Of Oxford
University Of Oxford
Affinity DataIC50: 33nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...More data for this Ligand-Target Pair
TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2 [F82H,L83V,H84D](Homo sapiens (Human))
University Of Oxford
University Of Oxford
Affinity DataIC50: 103nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...More data for this Ligand-Target Pair
TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2 [F82H,L83V,H84D,K98T](Homo sapiens (Human))
University Of Oxford
University Of Oxford
Affinity DataIC50: 120nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga...More data for this Ligand-Target Pair