Affinity DataIC50: 48nM Kd: 29nMpH: 8.4Assay Description:Inhibitory activity of the compounds for CAII was measured and IC50 values were calculated from independent triplicated experiments. Kd values were ...More data for this Ligand-Target Pair
Affinity DataIC50: 72nM Kd: 100nMpH: 8.4Assay Description:Inhibitory activity of the compounds for CAII was measured and IC50 values were calculated from independent triplicated experiments. Kd values were ...More data for this Ligand-Target Pair
Affinity DataIC50: 137nM Kd: 208nMpH: 8.4Assay Description:Inhibitory activity of the compounds for CAII was measured and IC50 values were calculated from independent triplicated experiments. Kd values were ...More data for this Ligand-Target Pair
Affinity DataIC50: 203nM Kd: 435nMpH: 8.4Assay Description:Inhibitory activity of the compounds for CAII was measured and IC50 values were calculated from independent triplicated experiments. Kd values were ...More data for this Ligand-Target Pair
Affinity DataIC50: 299nM Kd: 426nMpH: 8.4Assay Description:Inhibitory activity of the compounds for CAII was measured and IC50 values were calculated from independent triplicated experiments. Kd values were ...More data for this Ligand-Target Pair
Affinity DataKd: 45nMpH: 7.6 T: 2°CAssay Description:Dissociation constant of 667-coumate was measured for tight-binding inhibitors of CA II. The formation of the 4-nitrophenol was monitored at 348 nm f...More data for this Ligand-Target Pair
Affinity DataKd: 4.03E+3nMpH: 7.0 T: 2°CAssay Description:The dissociation constant of the hCA and inhibitor complex was determined by competitive displacement of a fixed concentration of dansylamide by incr...More data for this Ligand-Target Pair
Affinity DataKd: 200nMpH: 7.0 T: 2°CAssay Description:The dissociation constant of the hCA and inhibitor complex was determined by competitive displacement of a fixed concentration of dansylamide by incr...More data for this Ligand-Target Pair
Affinity DataKd: 76nMpH: 7.0 T: 2°CAssay Description:The dissociation constant of the hCA and inhibitor complex was determined by competitive displacement of a fixed concentration of dansylamide by incr...More data for this Ligand-Target Pair
Affinity DataKd: 230nMpH: 7.0 T: 2°CAssay Description:The dissociation constant of the hCA and inhibitor complex was determined by competitive displacement of a fixed concentration of dansylamide by incr...More data for this Ligand-Target Pair
Affinity DataKd: 120nMpH: 7.0 T: 2°CAssay Description:The dissociation constant of the hCA and inhibitor complex was determined by competitive displacement of a fixed concentration of dansylamide by incr...More data for this Ligand-Target Pair
Affinity DataKd: 660nMpH: 7.0 T: 2°CAssay Description:The dissociation constant of the hCA and inhibitor complex was determined by competitive displacement of a fixed concentration of dansylamide by incr...More data for this Ligand-Target Pair
Affinity DataKd: 235nMpH: 7.0 T: 2°CAssay Description:The dissociation constant of the hCA and inhibitor complex was determined by competitive displacement of a fixed concentration of dansylamide by incr...More data for this Ligand-Target Pair
Affinity DataKd: 80nMpH: 7.0 T: 2°CAssay Description:The dissociation constant of the hCA and inhibitor complex was determined by competitive displacement of a fixed concentration of dansylamide by incr...More data for this Ligand-Target Pair
Affinity DataKd: 27nMpH: 7.0 T: 2°CAssay Description:The dissociation constant of the hCA and inhibitor complex was determined by competitive displacement of a fixed concentration of dansylamide by incr...More data for this Ligand-Target Pair
Affinity DataKd: 28nMpH: 7.0 T: 2°CAssay Description:The dissociation constant of the hCA and inhibitor complex was determined by competitive displacement of a fixed concentration of dansylamide by incr...More data for this Ligand-Target Pair
Affinity DataKd: 0.460nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
Affinity DataKd: 0.490nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
Affinity DataKd: 0.830nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
Affinity DataKd: 0.200nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
Affinity DataKd: 0.160nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
Affinity DataKd: 0.320nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
Affinity DataKd: 0.130nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
Affinity DataKd: 0.100nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
Affinity DataKd: 0.100nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
Affinity DataKd: 1.70nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
Affinity DataKd: 0.130nMpH: 7.4 T: 2°CAssay Description:The binding of test compounds to purified human erythrocyte carbonic anhydrase II was determined by a fluorescence competition assay using a Perkin-E...More data for this Ligand-Target Pair
Affinity DataKd: 33nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 12nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 4.35E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 1.11E+4nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 10nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 5.88nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 9.09E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+4nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 8.33nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 10nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 5.00E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 7.14E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 143nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 8.33nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 2.50E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 8.33E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 8.33nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 4.76nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 4.76E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 7.14E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 7.14nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 2.86nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair