Compile Data Set for Download or QSAR
Report error Found 469 of kd data for polymerid = 5059,49000249,49000251,49000255,50000525,50002456,50002638
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81499BDBM81499(NSC_155346 | CYANOPINDOLOL | CAS_155346 | CYANOPIN...)
Affinity DataKd:  0.00100nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81499BDBM81499(NSC_155346 | CYANOPINDOLOL | CAS_155346 | CYANOPIN...)
Affinity DataKd:  0.00100nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232757BDBM50232757(CHEMBL4092412)
Affinity DataKd:  0.0182nMAssay Description:Partial agonist activity at human beta2-AR expressed in CHOK1 cells assessed as inhibition of cimaterol-induced CRE-SPAP production after 5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2019
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232766BDBM50232766(Berlafenone)
Affinity DataKd:  0.0350nMAssay Description:Displacement of [3H](-)CGP12177 from human beta2-AR expressed in CHOK1 cells after 2 hrs by TopCount microscintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2019
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232757BDBM50232757(CHEMBL4092412)
Affinity DataKd:  0.0355nMAssay Description:Displacement of [3H](-)CGP12177 from human beta2-AR expressed in CHOK1 cells after 2 hrs by TopCount microscintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2019
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601574BDBM50601574(CHEMBL5201074)
Affinity DataKd:  0.0700nMAssay Description:Displacement of [3H]CGP12177 from human beta-2 adrenergic receptor stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568740BDBM50568740(CHEMBL4860528)
Affinity DataKd:  0.0700nMAssay Description:Displacement of [3H]CGP12177 from human beta-2 adrenergic receptor stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601567BDBM50601567(CHEMBL5206565)
Affinity DataKd:  0.0700nMAssay Description:Displacement of [3H]CGP12177 from human beta-2 adrenergic receptor stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601551BDBM50601551(CHEMBL5207281)
Affinity DataKd:  0.0700nMAssay Description:Displacement of [3H]CGP12177 from human beta-2 adrenergic receptor stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25761BDBM25761(Propanolol,(+/-) | PROPRANOLOL, l- | PROPRANOLOL,(...)
Affinity DataKd:  0.100nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25761BDBM25761(Propanolol,(+/-) | PROPRANOLOL, l- | PROPRANOLOL,(...)
Affinity DataKd:  0.100nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25765BDBM25765(tert-butyl[3-(2-chloro-5-methylphenoxy)-2-hydroxyp...)
Affinity DataKd:  0.140nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25759BDBM25759([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...)
Affinity DataKd:  0.195nMAssay Description:Displacement of [3H]DHA from beta2 adrenergic receptor (unknown origin) stably expressed in HEK293 cell membranes measured after 90 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50027879BDBM50027879(CHEBI:73288 | CGP-12177)
Affinity DataKd:  0.200nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50027879BDBM50027879(CHEBI:73288 | CGP-12177)
Affinity DataKd:  0.200nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25767BDBM25767(tert-butyl(2-hydroxy-3-{[4-(morpholin-4-yl)-1,2,5-...)
Affinity DataKd:  0.210nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25761BDBM25761(Propanolol,(+/-) | PROPRANOLOL, l- | PROPRANOLOL,(...)
Affinity DataKd:  0.240nMAssay Description:Antagonist activity at human beta-2 adrenergic receptor expressed in salbutamol-stimulated CHO-K1 cells assessed as CRE-SPAP level by fluorescence co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50292219BDBM50292219((2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,...)
Affinity DataKd:  0.240nMAssay Description:In vitro beta-2 adrenergic receptor activity was determined by measuring inhibition of the isoproterenol induced relaxation in isolated guinea pig tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27960BDBM27960(CHEMBL198059 | (2R,3S)-1-[(7-methyl-2,3-dihydro-1H...)
Affinity DataKd:  0.245nMAssay Description:Displacement of [3H](-)CGP12177 from human beta2-AR expressed in CHOK1 cells after 2 hrs by TopCount microscintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2019
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421329BDBM50421329(CHEMBL2088201)
Affinity DataKd:  0.260nMAssay Description:Kinetic binding affinity to human beta2-adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50423821BDBM50423821(CHEMBL1830486)
Affinity DataKd:  0.275nMAssay Description:Antagonist activity at human beta-2 adrenergic receptor expressed in salbutamol-stimulated CHO-K1 cells assessed as CRE-SPAP level by fluorescence co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25764BDBM25764(ALPRENOLOL,(-) | CHEMBL266195 | ALPRENOLOL,(+) | A...)
Affinity DataKd:  0.295nMAssay Description:Antagonist activity at human beta-2 adrenergic receptor expressed in salbutamol-stimulated CHO-K1 cells assessed as CRE-SPAP level by fluorescence co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50423827BDBM50423827(CHEMBL1830491)
Affinity DataKd:  0.295nMAssay Description:Antagonist activity at human beta-2 adrenergic receptor expressed in salbutamol-stimulated CHO-K1 cells assessed as CRE-SPAP level by fluorescence co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25771BDBM25771(salmeterol xinafoate | 4-(1-hydroxy-2-{[6-(4-pheny...)
Affinity DataKd:  0.300nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25771BDBM25771(salmeterol xinafoate | 4-(1-hydroxy-2-{[6-(4-pheny...)
Affinity DataKd:  0.300nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50532364BDBM50532364(CHEMBL1233766)
Affinity DataKd:  0.300nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50532364BDBM50532364(CHEMBL1233766)
Affinity DataKd:  0.300nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Bovine)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421724BDBM50421724(SD-2124-01 | PROCINOLOL)
Affinity DataKd:  0.389nMAssay Description:Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Bovine)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421724BDBM50421724(SD-2124-01 | PROCINOLOL)
Affinity DataKd:  0.390nMAssay Description:Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25759BDBM25759([3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-met...)
Affinity DataKd:  0.400nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25747BDBM25747(4-[3-(tert-butylamino)-2-hydroxypropoxy]-2,3-dihyd...)
Affinity DataKd:  0.410nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50423824BDBM50423824(CHEMBL1830618)
Affinity DataKd:  0.427nMAssay Description:Antagonist activity at human beta-2 adrenergic receptor expressed in salbutamol-stimulated CHO-K1 cells assessed as CRE-SPAP level by fluorescence co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50423829BDBM50423829(CHEMBL1830485)
Affinity DataKd:  0.427nMAssay Description:Antagonist activity at human beta-2 adrenergic receptor expressed in salbutamol-stimulated CHO-K1 cells assessed as CRE-SPAP level by fluorescence co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50423826BDBM50423826(CHEMBL1830492)
Affinity DataKd:  0.437nMAssay Description:Antagonist activity at human beta-2 adrenergic receptor expressed in salbutamol-stimulated CHO-K1 cells assessed as CRE-SPAP level by fluorescence co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50493311BDBM50493311(rel-RITODRINE)
Affinity DataKd:  0.501nMAssay Description:Binding affinity to beta-2 adrenergic receptor (unknown origin) at 1 to 10000 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25764BDBM25764(ALPRENOLOL,(-) | CHEMBL266195 | ALPRENOLOL,(+) | A...)
Affinity DataKd:  0.501nMAssay Description:Displacement of [3H]-CGP 12177 from human beta-2 adrenergic receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019443BDBM50019443(LB-46 | 1-(1H-Indol-4-yloxy)-3-isopropylamino-prop...)
Affinity DataKd:  0.537nMAssay Description:Displacement of [3H]-CGP 12177 from human beta-2 adrenergic receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25768BDBM25768(ICI 118,551 | 1-[(7-methyl-2,3-dihydro-1H-inden-4-...)
Affinity DataKd:  0.550nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25761BDBM25761(Propanolol,(+/-) | PROPRANOLOL, l- | PROPRANOLOL,(...)
Affinity DataKd:  0.603nMAssay Description:Displacement of [3H]-CGP 12177 from human beta-2 adrenergic receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50423818BDBM50423818(CHEMBL1830619)
Affinity DataKd:  0.617nMAssay Description:Antagonist activity at human beta-2 adrenergic receptor expressed in salbutamol-stimulated CHO-K1 cells assessed as CRE-SPAP level by fluorescence co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50423827BDBM50423827(CHEMBL1830491)
Affinity DataKd:  0.617nMAssay Description:Displacement of [3H]-CGP 12177 from human beta-2 adrenergic receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Bovine)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81447BDBM81447(CAS_43216 | NSC_43216 | Dihydroalprenolol,(+/-))
Affinity DataKd:  0.630nMAssay Description:Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Bovine)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81447BDBM81447(CAS_43216 | NSC_43216 | Dihydroalprenolol,(+/-))
Affinity DataKd:  0.631nMAssay Description:Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019443BDBM50019443(LB-46 | 1-(1H-Indol-4-yloxy)-3-isopropylamino-prop...)
Affinity DataKd:  0.661nMAssay Description:Antagonist activity at human beta-2 adrenergic receptor expressed in salbutamol-stimulated CHO-K1 cells assessed as CRE-SPAP level by fluorescence co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25768BDBM25768(ICI 118,551 | 1-[(7-methyl-2,3-dihydro-1H-inden-4-...)
Affinity DataKd:  0.676nMAssay Description:Displacement of [3H]-CGP12177 from human beta2 adrenoceptor expressed in CHOK1 cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81499BDBM81499(NSC_155346 | CYANOPINDOLOL | CAS_155346 | CYANOPIN...)
Affinity DataKd:  0.700nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes assessed as intrinsic Kd by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81499BDBM81499(NSC_155346 | CYANOPINDOLOL | CAS_155346 | CYANOPIN...)
Affinity DataKd:  0.700nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes assessed as intrinsic Kd by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50365058BDBM50365058(CHEMBL1951067)
Affinity DataKd:  0.708nMAssay Description:Competitive antagonist activity at beta2-adrenoceptor in guinea pig tracheal ring in the presence of N-(5-((1R)-2-(4-(4-(3,4-dimethoxyphenol)-1-oxo-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50423821BDBM50423821(CHEMBL1830486)
Affinity DataKd:  0.724nMAssay Description:Displacement of [3H]-CGP 12177 from human beta-2 adrenergic receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50423821BDBM50423821(CHEMBL1830486)
Affinity DataKd:  0.741nMAssay Description:Antagonist activity at human beta-2 adrenergic receptor expressed in salbutamol-stimulated CHO-K1 cells assessed as CRE-SPAP level by fluorescence co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
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