Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 2001
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350315BDBM350315(US10208064, Example 30)
Affinity DataIC50: 6nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350299BDBM350299(US10208064, Example 18)
Affinity DataIC50: 7nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350282BDBM350282(US10208064, Example 2)
Affinity DataIC50: 9nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350300BDBM350300(US10208064, Example 19)
Affinity DataIC50: 10nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350301BDBM350301(US10208064, Example 20)
Affinity DataIC50: 11nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350289BDBM350289(US10208064, Example 8)
Affinity DataIC50: 13nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350296BDBM350296(US10208064, Example 15)
Affinity DataIC50: 14nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350305BDBM350305(US10208064, Example 24)
Affinity DataIC50: 16nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350304BDBM350304(US10208064, Example 23)
Affinity DataIC50: 17nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350312BDBM350312(8-(2-hydroxy-1-(tetrazolo[1,5-a]quinolin-7-yl)ethy...)
Affinity DataIC50: 18nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350302BDBM350302(US10208064, Example 21)
Affinity DataIC50: 19nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350290BDBM350290(US10208064, Example 9)
Affinity DataIC50: 19nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350298BDBM350298(US10208064, Example 17)
Affinity DataIC50: 20nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350294BDBM350294(US10208064, Example 13)
Affinity DataIC50: 23nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350309BDBM350309(8-(2-hydroxy-2-((R)-5-methyl-5H-tetrazolo[5,1-^...)
Affinity DataIC50: 27nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350311BDBM350311(8-((S)-2-hydroxy-2-((R)-5-methyl-5H-tetrazolo[5,1-...)
Affinity DataIC50: 29nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350281BDBM350281(US10208064, Example 1)
Affinity DataIC50: 31nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350297BDBM350297(US10208064, Example 16)
Affinity DataIC50: 32nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350287BDBM350287((R)-8-(2-(4,5-dihydrotetrazolo[1,5-a]quinolin-7-yl...)
Affinity DataIC50: 34nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350283BDBM350283(US10208064, Example 3)
Affinity DataIC50: 35nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350310BDBM350310(8-((R)-2-hydroxy-2-((R)-5-methyl-5H-tetrazolo[5,1-...)
Affinity DataIC50: 36nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350288BDBM350288((S)-8-(2-(4,5-dihydrotetrazolo[1,5-a]quinolin-7-yl...)
Affinity DataIC50: 38nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350286BDBM350286(US10208064, Example 6)
Affinity DataIC50: 40nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350284BDBM350284(US10208064, Example 4)
Affinity DataIC50: 43nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350313BDBM350313((S)-8-(2-hydroxy-1-(tetrazolo[1,5-a]quinolin-7-yl)...)
Affinity DataIC50: 44nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350291BDBM350291(US10208064, Example 10)
Affinity DataIC50: 46nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350292BDBM350292(US10208064, Example 11)
Affinity DataIC50: 47nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350307BDBM350307(US10208064, Example 26)
Affinity DataIC50: 82nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350308BDBM350308(8-(2-hydroxy-2-((S)-5-methyl-5H-tetrazolo[5,1-^...)
Affinity DataIC50: 87nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350285BDBM350285(US10208064, Example 5)
Affinity DataIC50: 111nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350306BDBM350306(US10208064, Example 25)
Affinity DataIC50: 128nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350303BDBM350303(US10208064, Example 22)
Affinity DataIC50: 185nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350293BDBM350293(US10208064, Example 12)
Affinity DataIC50: 188nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350316BDBM350316(US10208064, Example 31)
Affinity DataIC50: 239nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350295BDBM350295(US10208064, Example 14)
Affinity DataIC50: 284nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Wuxi Apptec (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 350314BDBM350314(US10208064, Example 29)
Affinity DataIC50: 421nMAssay Description:A Thallium Flux Assay was performed on the compounds of the Examples. This assay has been described previously; see, e.g., PCT Published Application ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent