Compile Data Set for Download or QSAR
Report error Found 86 Enz. Inhib. hit(s) with all data for entry = 10566
LigandPNGBDBM550793(US11311528, Ex. 1-83)
Affinity DataIC50: 10nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550527(US11311528, Ex. 1-2 | US11311528, Ex. 1-1)
Affinity DataIC50: 33nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM50521324(CHEMBL4554395 | US11311528, Ex. 1-77)
Affinity DataIC50: 41nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550527(US11311528, Ex. 1-2 | US11311528, Ex. 1-1)
Affinity DataIC50: 53nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550794(US11311528, Ex. 1-84)
Affinity DataIC50: 55nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM50521331(CHEMBL4557373 | US11311528, Ex. 1-85)
Affinity DataIC50: 68nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)
LigandPNGBDBM550772((3S,4S) or (3R,4R)-2-(4-tert-butyl-3- chlorophenyl...)
Affinity DataIC50: 95nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550770((3R,4R) or (3S,4S)-2-(4-tert-butyl-3- chlorophenyl...)
Affinity DataIC50: 106nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550777(US11311528, Ex. 1-67)
Affinity DataIC50: 122nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550765((3S,4S) and (3R,4R)-2-(4-tert-butyl-3- chloropheny...)
Affinity DataIC50: 135nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550762((3R,4R) or (3S,4S)-2-(3-chloro-4- cyclohexylphenyl...)
Affinity DataIC50: 186nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550784((3S,4S) or (3R,4R)-2-(4-tert-butyl-3- chlorophenyl...)
Affinity DataIC50: 209nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550758((3S,4S) and (3R,4R)-2-[3-chloro-4-(1- cyano-1-meth...)
Affinity DataIC50: 213nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550774((3R,4R) or (3S,4S)-2-[3-chloro-4-(1- cyanocyclopro...)
Affinity DataIC50: 225nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550764((3S,4S) and (3R,4R)-7-bromo-2-(4-tert- butyl-3-chl...)
Affinity DataIC50: 266nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550792(US11311528, Ex. 1-82)
Affinity DataIC50: 329nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550747((3R,4R) or (3S,4S)-3-(2,3-dihydro-1,4- benzodioxin...)
Affinity DataIC50: 339nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550739((3S,4S) and (3S,4R)-3-(2,3-dihydro-1,4- benzodioxi...)
Affinity DataIC50: 339nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM50521330(CHEMBL4450597 | US11311528, Ex. 1-76)
Affinity DataIC50: 357nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550791(US11311528, Ex. 1-81)
Affinity DataIC50: 441nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550789(US11311528, Ex. 1-79)
Affinity DataIC50: 482nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550750((3S,4S) or (3R,4R)-2-(3,4- dichlorophenyl)-3-(2,3-...)
Affinity DataIC50: 483nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550768((3R,4R) or (3S,4S)-2-(4-tert-butyl-3- chlorophenyl...)
Affinity DataIC50: 538nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550763((3R,4R) and (3S,4S)-2-(4-tert-butyl-3- chloropheny...)
Affinity DataIC50: 602nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550790(US11311528, Ex. 1-80)
Affinity DataIC50: 602nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550738(US11311528, Ex. 1-36 | (3S,4S) and (3S,4R)-2-[4-(1...)
Affinity DataIC50: 669nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM50521335(CHEMBL4588504 | US11311528, Ex. 1-78)
Affinity DataIC50: 670nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550709((3S,4S) or (3R,4R)-3-(2,3-dihydro-1,4- benzodioxin...)
Affinity DataIC50: 732nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550782((3S,4S) or (3R,4R)-2-(4-tert-butyl-3- chlorophenyl...)
Affinity DataIC50: 737nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550738(US11311528, Ex. 1-36 | (3S,4S) and (3S,4R)-2-[4-(1...)
Affinity DataIC50: 803nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550753((3S,4S) and (3R,4R)-2-(4-cyclopropyl-3- fluorophen...)
Affinity DataIC50: 828nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550733((3S,4S) and (3R,4R)-2-(3-chloro-4- morpholin-4-ylp...)
Affinity DataIC50: 858nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550742((3S,4S) and (3R,4R)-2-(2-chloro-6- methylpyridin-4...)
Affinity DataIC50: 952nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550757((3S,4S) and (3R,4R)-3-(2,3-dihydro-1,4- benzodioxi...)
Affinity DataIC50: 1.14E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550708((3R,4R) or (3S,4S)-3-(2,3-dihydro-1,4- benzodioxin...)
Affinity DataIC50: 1.16E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550796(US11311528, Ex. 1-86)
Affinity DataIC50: 1.22E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550741((3S,4S) and (3R,4R)-3-(2,3-dihydro-1,4- benzodioxi...)
Affinity DataIC50: 1.22E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550752((3S,4S) and (3R,4R)-2-(3-bromophenyl)- 3-(2,3-dihy...)
Affinity DataIC50: 1.24E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550760((3S,4S) and (3R,4R)-7-bromo-2-(3- chloro-4-methylp...)
Affinity DataIC50: 1.29E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550778((3R,4R) and (3S,4S)-2-[4-(1- acetylpiperidin-4-yl)...)
Affinity DataIC50: 1.47E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550714((3R,4R) and (3S,4S)-2-(2-chloropyridin- 4-yl)-3-(2...)
Affinity DataIC50: 1.52E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550775(US11311528, Ex. 1-65)
Affinity DataIC50: 1.56E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550751((3S,4S) and (3R,4R)-2-[4-(benzyloxy)-3- chlorophen...)
Affinity DataIC50: 1.57E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550730((3S,4S) and (3R,4R)-2-[3-chloro-4- (difluoromethox...)
Affinity DataIC50: 1.63E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550756((3S,4S) and (3R,4R)-3-(2,3-dihydro-1,4- benzodioxi...)
Affinity DataIC50: 1.80E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550780((3R,4R) and (3S,4S)-2-{4-[trans-4- (acetylamino)cy...)
Affinity DataIC50: 1.93E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550732((3S,4S) and (3R,4R)-2-(3-chlorophenyl)- 3-(2,3-dih...)
Affinity DataIC50: 2.24E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550729((3S,4S) and (3R,4R)-2-(3-cyano-4- morpholin-4-ylph...)
Affinity DataIC50: 2.28E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550737((3S,4S) and (3R,4R)-2-(4- cyclohexylphenyl)-3-(2,3...)
Affinity DataIC50: 2.96E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550713((3R,4R) and (3S,4S) (-2-[4-(1-cyano-1- methylethyl...)
Affinity DataIC50: 2.97E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

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