Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50010323
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50093336(6-(Thiophen-2-yloxy)-9H-purin-2-ylamine | CHEMBL33...)
Affinity DataIC50: 3nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5491(6-(benzyloxy)-9H-purin-2-amine | CHEMBL407874 | O6...)
Affinity DataIC50: 58nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5491(6-(benzyloxy)-9H-purin-2-amine | CHEMBL407874 | O6...)
Affinity DataIC50: 180nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5484(6-(cyclopent-1-en-1-ylmethoxy)-9H-purin-2-amine | ...)
Affinity DataIC50: 200nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5484(6-(cyclopent-1-en-1-ylmethoxy)-9H-purin-2-amine | ...)
Affinity DataIC50: 390nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50093328(6-(Cyclobut-1-enylmethoxy)-9H-purin-2-ylamine | CH...)
Affinity DataIC50: 550nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5486(6-(cyclohex-1-en-1-ylmethoxy)-9H-purin-2-amine | C...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50241513(6-(4-Isopropenyl-cyclohex-1-enylmethoxy)-9H-purin-...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5475(CHEMBL325053 | 6-(prop-2-en-1-yloxy)-9H-purin-2-am...)
Affinity DataIC50: 2.70E+3nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5475(CHEMBL325053 | 6-(prop-2-en-1-yloxy)-9H-purin-2-am...)
Affinity DataIC50: 5.10E+3nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5475(CHEMBL325053 | 6-(prop-2-en-1-yloxy)-9H-purin-2-am...)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5472(6-(prop-2-yn-1-yloxy)-9H-purin-2-amine | CHEMBL270...)
Affinity DataIC50: 1.15E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5472(6-(prop-2-yn-1-yloxy)-9H-purin-2-amine | CHEMBL270...)
Affinity DataIC50: 1.19E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5476(6-[(2-methylprop-2-en-1-yl)oxy]-9H-purin-2-amine |...)
Affinity DataIC50: 1.35E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5476(6-[(2-methylprop-2-en-1-yl)oxy]-9H-purin-2-amine |...)
Affinity DataIC50: 1.35E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5477(6-(2-methylidenebutoxy)-9H-purin-2-amine | CHEMBL2...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5472(6-(prop-2-yn-1-yloxy)-9H-purin-2-amine | CHEMBL270...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5476(6-[(2-methylprop-2-en-1-yl)oxy]-9H-purin-2-amine |...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5479(CHEMBL334050 | 6-[(2-phenylprop-2-en-1-yl)oxy]-9H-...)
Affinity DataIC50: 3.75E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5479(CHEMBL334050 | 6-[(2-phenylprop-2-en-1-yl)oxy]-9H-...)
Affinity DataIC50: 3.96E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5479(CHEMBL334050 | 6-[(2-phenylprop-2-en-1-yl)oxy]-9H-...)
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50093325(1-(2-Amino-9H-purin-6-yloxy)-butan-2-one | CHEMBL3...)
Affinity DataIC50: 9.32E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50093325(1-(2-Amino-9H-purin-6-yloxy)-butan-2-one | CHEMBL3...)
Affinity DataIC50: 9.45E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5481(CHEMBL272689 | 1-[(2-amino-9H-purin-6-yl)oxy]propa...)
Affinity DataIC50: 9.50E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5481(CHEMBL272689 | 1-[(2-amino-9H-purin-6-yl)oxy]propa...)
Affinity DataIC50: 9.50E+4nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5464(CHEMBL270945 | 6-(heptyloxy)-9H-purin-2-amine | O6...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50093325(1-(2-Amino-9H-purin-6-yloxy)-butan-2-one | CHEMBL3...)
Affinity DataIC50: 1.51E+5nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5481(CHEMBL272689 | 1-[(2-amino-9H-purin-6-yl)oxy]propa...)
Affinity DataIC50: 1.92E+5nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5470(CHEMBL226395 | 6-methoxy-9H-purin-2-amine | O6-Sub...)
Affinity DataIC50: 2.48E+5nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in intact HT-29 human colorectal carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5470(CHEMBL226395 | 6-methoxy-9H-purin-2-amine | O6-Sub...)
Affinity DataIC50: 4.28E+5nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5462(CHEMBL270946 | 6-butoxy-9H-purin-2-amine | O6-Subs...)
Affinity DataIC50: 4.93E+5nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5496(CHEMBL446625 | 6-(2-phenylethoxy)-9H-purin-2-amine...)
Affinity DataIC50: 5.48E+5nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50093343(6-Hexyloxy-9H-purin-2-ylamine | CHEMBL338451)
Affinity DataIC50: 5.54E+5nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5469(CHEMBL269872 | 6-(3-methylbutoxy)-9H-purin-2-amine...)
Affinity DataIC50: 1.00E+6nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in HT-29 cell extract.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50093331(2-(2-Amino-9H-purin-6-yloxy)-1-phenyl-ethanone | C...)
Affinity DataIC50: 1.00E+6nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in HT-29 cell extract.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50093347(6-Hex-3-enyloxy-9H-purin-2-ylamine | CHEMBL129960)
Affinity DataIC50: 1.00E+6nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in HT-29 cell extract.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50241514(6-(2,2-Dimethyl-[1,3]dioxolan-4-ylmethoxy)-9H-puri...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5501(CHEMBL405533 | 6-(2,2-diethoxypropoxy)-9H-purin-2-...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50093345(6-(2,2-Dimethoxy-2-phenyl-ethoxy)-9H-purin-2-ylami...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5485(6-(cyclohexylmethoxy)-9H-purin-2-amine | CHEMBL269...)
Affinity DataIC50: 1.00E+6nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in HT-29 cell extract.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5502(6-(2,2-dimethoxybutoxy)-9H-purin-2-amine | CHEMBL4...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5461(6-propoxy-9H-purin-2-amine | CHEMBL272692 | O6-Sub...)
Affinity DataIC50: 1.00E+6nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in HT-29 cell extract.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5487(CHEMBL115498 | 6-(cyclohex-3-en-1-ylmethoxy)-9H-pu...)
Affinity DataIC50: 1.00E+6nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in HT-29 cell extract.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50093340(6-Cyclobutylmethoxy-9H-purin-2-ylamine | CHEMBL133...)
Affinity DataIC50: 1.00E+6nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in HT-29 cell extract.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5471(6-ethoxy-9H-purin-2-amine | CHEMBL406419 | O6-Subs...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5483(6-(cyclopentylmethoxy)-9H-purin-2-amine | CHEMBL27...)
Affinity DataIC50: 1.00E+6nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in HT-29 cell extract.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5482(1-[(2-amino-9H-purin-6-yl)oxy]-3-methylbutan-2-one...)
Affinity DataIC50: 1.00E+6nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in HT-29 cell extract.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5478(CHEMBL407877 | 6-(3-methyl-2-methylidenebutoxy)-9H...)
Affinity DataIC50: 1.00E+6nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in HT-29 cell extract.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5463(CHEMBL406495 | 6-(pentyloxy)-9H-purin-2-amine | O6...)
Affinity DataIC50: 1.01E+6nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed