Compile Data Set for Download or QSAR
maximum 50k data
Found 192 Enz. Inhib. hit(s) with all data for entry = 1789
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14142(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-phe...)
Affinity DataKi:  8nM ΔG°:  -45.7kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14152(6-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-C...)
Affinity DataKi:  9nM ΔG°:  -45.5kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14149(6-fluoro-2-(2-hydroxy-3-{[(1S,2S)-2-methylcyclohex...)
Affinity DataKi:  11nM ΔG°:  -45.0kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14150(APC-11417 | CA-12 | CRA-11417 | {amino[6-fluoro-2-...)
Affinity DataKi:  20nM ΔG°:  -43.5kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14149(6-fluoro-2-(2-hydroxy-3-{[(1S,2S)-2-methylcyclohex...)
Affinity DataKi:  25nM ΔG°:  -43.0kJ/molepH: 8.2 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
Axys Pharmaceutical

LigandPNGBDBM14145(2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2...)
Affinity DataKi:  26nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14142(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-phe...)
Affinity DataKi:  35nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14146(APC-9008 | {amino[2-(3,5-dichloro-2-hydroxyphenyl)...)
Affinity DataKi:  70nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14156(3-bromo-N-(4-carbamimidoylphenyl)-2-hydroxy-5-meth...)
Affinity DataKi:  77nM ΔG°:  -40.2kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14142(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-phe...)
Affinity DataKi:  78nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14142(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-phe...)
Affinity DataKi:  100nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14152(6-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-C...)
Affinity DataKi:  110nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14148(2-{5-[amino(iminiumyl)methyl]-6-fluoro-1H-1,3-benz...)
Affinity DataKi:  110nM ΔG°:  -39.3kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Axys Pharmaceutical

LigandPNGBDBM14142(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-phe...)
Affinity DataKi:  130nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14149(6-fluoro-2-(2-hydroxy-3-{[(1S,2S)-2-methylcyclohex...)
Affinity DataKi:  140nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14156(3-bromo-N-(4-carbamimidoylphenyl)-2-hydroxy-5-meth...)
Affinity DataKi:  150nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Axys Pharmaceutical

LigandPNGBDBM14143(2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXA...)
Affinity DataKi:  150nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14148(2-{5-[amino(iminiumyl)methyl]-6-fluoro-1H-1,3-benz...)
Affinity DataKi:  160nM ΔG°:  -38.4kJ/molepH: 8.2 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14143(2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXA...)
Affinity DataKi:  160nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14145(2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2...)
Affinity DataKi:  180nM ΔG°:  -38.1kJ/molepH: 8.2 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14157(APC-10605 | CHEMBL64097 | N-(4-carbamimidoylphenyl...)
Affinity DataKi:  190nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14146(APC-9008 | {amino[2-(3,5-dichloro-2-hydroxyphenyl)...)
Affinity DataKi:  200nM ΔG°:  -37.9kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14146(APC-9008 | {amino[2-(3,5-dichloro-2-hydroxyphenyl)...)
Affinity DataKi:  210nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14144(2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2...)
Affinity DataKi:  220nM ΔG°:  -37.6kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
Axys Pharmaceutical

LigandPNGBDBM14152(6-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-C...)
Affinity DataKi:  230nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14147(APC-10818 | {amino[6-fluoro-2-(2-hydroxy-3-phenylp...)
Affinity DataKi:  250nM ΔG°:  -37.3kJ/molepH: 8.2 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14158(APC-11922 | CHEMBL293260 | N-(4-carbamimidoyl-3-fl...)
Affinity DataKi:  270nM ΔG°:  -37.1kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Axys Pharmaceutical

LigandPNGBDBM14156(3-bromo-N-(4-carbamimidoylphenyl)-2-hydroxy-5-meth...)
Affinity DataKi:  280nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14156(3-bromo-N-(4-carbamimidoylphenyl)-2-hydroxy-5-meth...)
Affinity DataKi:  290nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14143(2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXA...)
Affinity DataKi:  290nM ΔG°:  -36.9kJ/molepH: 8.2 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14143(2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXA...)
Affinity DataKi:  300nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14151(APC-9850 | {amino[6-chloro-2-(3,5-dichloro-2-hydro...)
Affinity DataKi:  310nM ΔG°:  -36.8kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14142(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-phe...)
Affinity DataKi:  320nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14157(APC-10605 | CHEMBL64097 | N-(4-carbamimidoylphenyl...)
Affinity DataKi:  330nM ΔG°:  -36.6kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14150(APC-11417 | CA-12 | CRA-11417 | {amino[6-fluoro-2-...)
Affinity DataKi:  350nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14146(APC-9008 | {amino[2-(3,5-dichloro-2-hydroxyphenyl)...)
Affinity DataKi:  350nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14145(2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2...)
Affinity DataKi:  370nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14145(2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2...)
Affinity DataKi:  390nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14158(APC-11922 | CHEMBL293260 | N-(4-carbamimidoyl-3-fl...)
Affinity DataKi:  410nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14156(3-bromo-N-(4-carbamimidoylphenyl)-2-hydroxy-5-meth...)
Affinity DataKi:  410nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14143(2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXA...)
Affinity DataKi:  430nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14143(2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXA...)
Affinity DataKi:  450nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14143(2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXA...)
Affinity DataKi:  450nM ΔG°:  -35.9kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14145(2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2...)
Affinity DataKi:  480nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14154(2-{5-[amino(iminiumyl)methyl]-6-chloro-1H-1,3-benz...)
Affinity DataKi:  490nM ΔG°:  -35.7kJ/molepH: 8.2 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14145(2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2...)
Affinity DataKi:  500nM ΔG°:  -35.6kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14158(APC-11922 | CHEMBL293260 | N-(4-carbamimidoyl-3-fl...)
Affinity DataKi:  500nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14157(APC-10605 | CHEMBL64097 | N-(4-carbamimidoylphenyl...)
Affinity DataKi:  530nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14147(APC-10818 | {amino[6-fluoro-2-(2-hydroxy-3-phenylp...)
Affinity DataKi:  550nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14144(2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2...)
Affinity DataKi:  550nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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