Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50012898
TargetCalpain-1 catalytic subunit(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: 7.5nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124017(N-(1-Formyl-3-methyl-butyl)-3-methyl-2-(naphthalen...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124024(2-(4-Chloro-benzenesulfonylamino)-N-[1-formyl-2-(1...)
Affinity DataIC50: 13nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124012(2-(4-Chloro-benzenesulfonylamino)-N-(1-formyl-2-ph...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124022(N-(1-Formyl-2-phenyl-ethyl)-3-methyl-2-(naphthalen...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124019(N-(1-Formyl-2-phenyl-ethyl)-3-methyl-2-(toluene-4-...)
Affinity DataIC50: 18nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124018(2-(4-Fluoro-benzenesulfonylamino)-N-[1-formyl-2-(1...)
Affinity DataIC50: 23nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124023(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-2-ph...)
Affinity DataIC50: 27nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124015(N-(1-Formyl-3-methyl-butyl)-3-methyl-2-(toluene-4-...)
Affinity DataIC50: 28nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124014(2-(4-Chloro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: 31nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: 78nMAssay Description:Inhibitory activity against Cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124016(2-(4-Fluoro-benzenesulfonylamino)-4-methyl-pentano...)
Affinity DataIC50: 130nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124021(2-(4-Fluoro-benzenesulfonylamino)-5-methyl-hexanoi...)
Affinity DataIC50: 260nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124025(2-(4-Fluoro-benzenesulfonylamino)-3-methyl-N-(1-me...)
Affinity DataIC50: 630nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124020(N-(1-Formyl-3-methyl-butyl)-2-methanesulfonylamino...)
Affinity DataIC50: 830nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50358145(CHEMBL1923968)
Affinity DataIC50: 1.40E+4nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124013(2-[(4-Fluoro-benzenesulfonyl)-methyl-amino]-N-(1-f...)
Affinity DataIC50: 2.10E+4nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of Cytochrome P450 3A4 as BFC substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against interleukin 1-beta converting enzyme (IL-1 beta converting enzyme)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: 1.77E+5nMAssay Description:Inhibition of Cytochrome P450 2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory activity against ChymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: 2.91E+5nMAssay Description:Inhibition of Cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: 4.92E+5nMAssay Description:Inhibition of Cytochrome P450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: 5.31E+5nMAssay Description:Inhibition of Cytochrome P450 3A4 as BQ substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50358146(CHEMBL1923969)
Affinity DataIC50: 1.00E+6nMAssay Description:In vitro inhibition of porcine mu-calpain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50124010(2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-me...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Cytochrome P450 1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed