Compile Data Set for Download or QSAR
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Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50018717
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198429((S)-(4-(4-(2,4-dichlorobenzylamino)pyrido[2,3-d]py...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at human CCR4 expressed in CEMS529 cells assessed as effect on calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198429((S)-(4-(4-(2,4-dichlorobenzylamino)pyrido[2,3-d]py...)
Affinity DataIC50:  7nMAssay Description:Inhibition of MDC-induced chemotaxis in L1.2 cells expressing CCR4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198429((S)-(4-(4-(2,4-dichlorobenzylamino)pyrido[2,3-d]py...)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175665((R)-(4-(4-(2,4-dichlorobenzylamino)pyrimidin-2-yl)...)
Affinity DataIC50:  50nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198423((S)-(4-(4-(2,4-dichlorobenzylamino)pyrido[2,3-d]py...)
Affinity DataIC50:  80nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198433(CHEMBL397028 | N4-(2,4-dichlorobenzyl)-N2-(5-(diet...)
Affinity DataIC50:  140nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198425(1-(2,4-dichlorobenzyl)-N-(5-(diethylamino)pentan-2...)
Affinity DataIC50:  280nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198426(CHEMBL233047 | N4-(2,4-dichlorobenzyl)-N2-(4-(diet...)
Affinity DataIC50:  280nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198426(CHEMBL233047 | N4-(2,4-dichlorobenzyl)-N2-(4-(diet...)
Affinity DataIC50:  300nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198427(CHEMBL233045 | N4-(2,4-dichlorobenzyl)-N2-(5-(diet...)
Affinity DataIC50:  500nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198426(CHEMBL233047 | N4-(2,4-dichlorobenzyl)-N2-(4-(diet...)
Affinity DataIC50:  800nMAssay Description:Antagonist activity at human CCR4 expressed in CEMS529 cells assessed as effect on calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198430(9-(2,4-dichlorobenzyl)-N-(5-(diethylamino)pentan-2...)
Affinity DataIC50:  820nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198436(7-(2,4-dichlorobenzyl)-N-(5-(diethylamino)pentan-2...)
Affinity DataIC50:  830nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198428(CHEMBL396786 | N6-(2,4-dichlorobenzyl)-N2-(5-(diet...)
Affinity DataIC50:  1.10E+3nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198431(CHEMBL232841 | N2-(2,4-dichlorobenzyl)-N4-(5-(diet...)
Affinity DataIC50:  1.91E+3nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198435(CHEMBL232639 | N2-(2,4-dichlorobenzyl)-N6-(5-(diet...)
Affinity DataIC50:  2.10E+3nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198434(CHEMBL232641 | N2-(2,4-dichlorobenzyl)-N6-(5-(diet...)
Affinity DataIC50:  2.60E+3nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198424(CHEMBL233261 | N2-(2,4-dichlorobenzyl)-N4-(5-(diet...)
Affinity DataIC50:  3.60E+3nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198432(CHEMBL232640 | N6-(2,4-dichlorobenzyl)-N2-(5-(diet...)
Affinity DataIC50:  4.90E+3nMAssay Description:Displacement of [125I]MDC from human CCR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198426(CHEMBL233047 | N4-(2,4-dichlorobenzyl)-N2-(4-(diet...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of MDC-induced chemotaxis in L1.2 cells expressing CCR4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50198429((S)-(4-(4-(2,4-dichlorobenzylamino)pyrido[2,3-d]py...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed