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Found
85
Enz. Inhib. hit(s) with all data for entry = 4716
Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
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Affinity Data
Ki: 0.0300nM
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In Depth
Date in BDB:
11/18/2011
Entry Details
Article
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
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Affinity Data
Ki: 0.0500nM
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In Depth
Date in BDB:
11/18/2011
Entry Details
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Target
D(4) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
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Affinity Data
Ki: 0.0500nM
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Date in BDB:
11/18/2011
Entry Details
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
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Affinity Data
Ki: 0.0530nM
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In Depth
Date in BDB:
11/18/2011
Entry Details
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50005120
(Nemonapride | N-((2S,3S)-1-Benzyl-2-methyl-pyrroli...)
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Ki: 0.0600nM
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Date in BDB:
11/18/2011
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
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Affinity Data
Ki: 0.0690nM
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Date in BDB:
11/18/2011
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Target
D(4) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
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Affinity Data
Ki: 0.0800nM
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Date in BDB:
11/18/2011
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50005120
(Nemonapride | N-((2S,3S)-1-Benzyl-2-methyl-pyrroli...)
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Affinity Data
Ki: 0.0900nM
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In Depth
Date in BDB:
11/18/2011
Entry Details
Article
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50005120
(Nemonapride | N-((2S,3S)-1-Benzyl-2-methyl-pyrroli...)
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Affinity Data
Ki: 0.0900nM
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In Depth
Date in BDB:
11/18/2011
Entry Details
Article
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50007518
(3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmet...)
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Ki: 0.0900nM
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Date in BDB:
11/18/2011
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81793
(NSC_92178 | CAS_316-81-4 | Thioproperazine)
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Ki: 0.210nM
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Date in BDB:
11/18/2011
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81777
(NPA,(+) | NPA | CAS_132-66-1 | NSC_8594 | NPA,(-))
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Affinity Data
Ki: 0.400nM
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Date in BDB:
11/18/2011
Entry Details
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81872
(NSC_161309 | CAS_161309 | Ergocryptine, beta)
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Ki: 0.400nM
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Date in BDB:
11/18/2011
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Ki: 0.5nM
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Date in BDB:
11/18/2011
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM78433
(2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...)
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Ki: 0.5nM
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Date in BDB:
11/18/2011
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50007568
(CHEMBL303313 | 1-(8-Chloro-10,11-dihydro-dibenzo[b...)
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Ki: 0.600nM
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Date in BDB:
11/18/2011
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50054062
(CHEMBL104383 | N-0437 | 6-[Propyl-(2-thiophen-2-yl...)
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Affinity Data
Ki: 0.700nM
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In Depth
Date in BDB:
11/18/2011
Entry Details
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Affinity Data
Ki: 0.800nM
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In Depth
Date in BDB:
11/18/2011
Entry Details
Article
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50008735
(CHEMBL8514 | BUTACLAMOL,d- | (+)-3-(tert-butyl)-(3...)
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Affinity Data
Ki: 0.800nM
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CHEMBL
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In Depth
Date in BDB:
11/18/2011
Entry Details
Article
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PubMed
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Affinity Data
Ki: 1nM
More data for this Ligand-Target Pair
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Date in BDB:
11/18/2011
Entry Details
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PubMed
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50020217
(CHEMBL69271 | PHNO,(+) | 4-Propyl-3,4,4a,5,6,10b-h...)
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Ki: 1.20nM
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Date in BDB:
11/18/2011
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM79181
(cid_2913535 | TRIFLUOPERAZINE | SMR000059133 | MLS...)
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Ki: 1.20nM
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Date in BDB:
11/18/2011
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
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Ki: 1.5nM
More data for this Ligand-Target Pair
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Date in BDB:
11/18/2011
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50007568
(CHEMBL303313 | 1-(8-Chloro-10,11-dihydro-dibenzo[b...)
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Ki: 1.5nM
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In Depth
Date in BDB:
11/18/2011
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50007567
(CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...)
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Ki: 1.60nM
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Date in BDB:
11/18/2011
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81195
(cid_3153 | 6-Amino-5,6,7,8-tetrahydro-naphthalene-...)
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Ki: 1.70nM
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In Depth
Date in BDB:
11/18/2011
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50005118
(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
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Ki: 1.80nM
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In Depth
Date in BDB:
11/18/2011
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001955
(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
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Affinity Data
Ki: 2nM
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In Depth
Date in BDB:
11/18/2011
Entry Details
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50007518
(3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmet...)
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Ki: 2.10nM
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In Depth
Date in BDB:
11/18/2011
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50334150
(1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...)
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Ki: 2.40nM
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Date in BDB:
11/18/2011
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
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Ki: 2.80nM
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Date in BDB:
11/18/2011
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
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Ki: 2.80nM
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Date in BDB:
11/18/2011
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3D Structure (crystal)
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM60917
(MLS001401388 | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,...)
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Ki: 2.80nM
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Date in BDB:
11/18/2011
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM79181
(cid_2913535 | TRIFLUOPERAZINE | SMR000059133 | MLS...)
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Ki: 3nM
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Date in BDB:
11/18/2011
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50005118
(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
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Affinity Data
Ki: 3.20nM
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In Depth
Date in BDB:
11/18/2011
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50002338
(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
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Ki: 3.30nM
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In Depth
Date in BDB:
11/18/2011
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Copy BDB DOI
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50001955
(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
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Affinity Data
Ki: 4.10nM
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In Depth
Date in BDB:
11/18/2011
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM84637
(NSC_54562 | CHEMBL240773 | QUINPIROLE | CAS_85760-...)
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Ki: 4.80nM
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In Depth
Date in BDB:
11/18/2011
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81774
(Sulpiride-S | CAS_15676-16-1 | Sulpiride-l | SULPI...)
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Ki: 4.80nM
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Date in BDB:
11/18/2011
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Target
D(4) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Ki: 5.10nM
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Date in BDB:
11/18/2011
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
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Ligand
BDBM81993
(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)
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Ki: 5.30nM
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Date in BDB:
11/18/2011
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
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Ligand
BDBM81777
(NPA,(+) | NPA | CAS_132-66-1 | NSC_8594 | NPA,(-))
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Ki: 6.5nM
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Date in BDB:
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
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Ligand
BDBM55121
(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
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Ki: 7.5nM
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Date in BDB:
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
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Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
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Ki: 9nM
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Date in BDB:
11/18/2011
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Target
D(2) dopamine receptor
(Rat)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81774
(Sulpiride-S | CAS_15676-16-1 | Sulpiride-l | SULPI...)
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Ki: 9.20nM
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Date in BDB:
11/18/2011
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
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Ligand
BDBM50005118
(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
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Ki: 10.5nM
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Date in BDB:
11/18/2011
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Target
D(4) dopamine receptor
(Rat)
University of Toronto
Curated by
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i
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Ligand
BDBM50002338
(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
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Ki: 12nM
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Date in BDB:
11/18/2011
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Target
D(2) dopamine receptor
(Human)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM81993
(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)
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Ki: 12.6nM
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Date in BDB:
11/18/2011
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50007567
(CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...)
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Ki: 13.5nM
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Date in BDB:
11/18/2011
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Target
Dopamine receptor D4
(Dog)
University of Toronto
Curated by
PDSP K
i
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Ligand
BDBM81195
(cid_3153 | 6-Amino-5,6,7,8-tetrahydro-naphthalene-...)
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Ki: 24nM
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Date in BDB:
11/18/2011
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