Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 50026139
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50272012(1-(3-fluoro-4-(2-(pyridin-3-yl)-1H-pyrrolo[2,3-b]p...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50272049(1-(4-(2-amino-3-ethynylpyridin-4-yloxy)-3-fluoroph...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50271981(1-(3-fluoro-4-(3-(pyridin-3-yl)-1H-pyrrolo[2,3-b]p...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50272013(1-(4-(2-amino-3-(3-hydroxyprop-1-ynyl)pyridin-4-yl...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50271979(1-(3-fluoro-4-(3-(hydroxymethyl)-1H-pyrrolo[2,3-b]...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50272014(1-(4-(2-amino-3-(3-(dimethylamino)prop-1-ynyl)pyri...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50271978(CHEMBL499885 | methyl 4-(2-fluoro-4-(3-(2-(4-fluor...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50272015(1-(4-(2-amino-3-(2-(pyridin-2-yl)ethynyl)pyridin-4...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50272050(1-(4-(2-amino-3-(3-aminoprop-1-ynyl)pyridin-4-ylox...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50271980(1-(4-(3-(2-aminothiazol-4-yl)-1H-pyrrolo[2,3-b]pyr...)
Affinity DataIC50:  7nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50271943(1-(3-fluoro-4-(3-(2-(4-methylpiperazin-1-yl)acetyl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50271944(1-(4-(3-((pyridin-3-ylmethyl)carbamoyl)-1H-pyrrolo...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50271942(1-(3-fluoro-4-(3-(2-(3-hydroxypyrrolidin-1-yl)acet...)
Affinity DataIC50:  19nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50271940(1-(4-(2-aminopyridin-4-yloxy)-3-fluorophenyl)-3-(2...)
Affinity DataIC50:  35nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50271941(1-(4-(3-(2-(dimethylamino)acetyl)-1H-pyrrolo[2,3-b...)
Affinity DataIC50:  44nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50271894(CHEMBL500921 | N1-(4-(1H-pyrrolo[2,3-b]pyridin-4-y...)
Affinity DataIC50:  64nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50271939(CHEMBL499618 | N1-(4-(2-aminopyridin-4-yloxy)-3-fl...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50271895(1-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluoroph...)
Affinity DataIC50:  110nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50272013(1-(4-(2-amino-3-(3-hydroxyprop-1-ynyl)pyridin-4-yl...)
Affinity DataIC50:  700nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50235542(CHEMBL253223 | N1-(3-fluoro-4-(5-methylpyrrolo[1,2...)
Affinity DataIC50:  780nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50272049(1-(4-(2-amino-3-ethynylpyridin-4-yloxy)-3-fluoroph...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50272050(1-(4-(2-amino-3-(3-aminoprop-1-ynyl)pyridin-4-ylox...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50272014(1-(4-(2-amino-3-(3-(dimethylamino)prop-1-ynyl)pyri...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50272015(1-(4-(2-amino-3-(2-(pyridin-2-yl)ethynyl)pyridin-4...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed