Compile Data Set for Download or QSAR
Report error Found 66 Enz. Inhib. hit(s) with all data for entry = 50030988
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304836BDBM50304836(1,2-dimethyl-4-(6-methylpyridin-2-yl)-5-(quinoxali...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304849BDBM50304849(4-(3-ethylphenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304835BDBM50304835(1,2-dimethyl-4-(pyridin-2-yl)-5-(quinoxalin-6-yl)-...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304864BDBM50304864(4-(3-bromophenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304850BDBM50304850(1,2-dimethyl-5-(quinoxalin-6-yl)-4-(3-vinylphenyl)...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110208BDBM50110208(SB-431542 | cid_4521392 | 4-(5-(benzo[d][1,3]dioxo...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304863BDBM50304863(4-(3-chlorophenyl)-1,2-dimethyl-5-(quinoxalin-6-yl...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304865BDBM50304865(N-(3-(1,2-dimethyl-3-oxo-5-(quinoxalin-6-yl)-2,3-d...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304853BDBM50304853(4-(3-methoxyphenyl)-1,2-dimethyl-5-(quinoxalin-6-y...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304840BDBM50304840(1,2-dimethyl-5-(quinoxalin-6-yl)-4-m-tolyl-1H-pyra...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304858BDBM50304858(2-(3-(1,2-dimethyl-3-oxo-5-(quinoxalin-6-yl)-2,3-d...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304855BDBM50304855(4-(3-(methoxymethyl)phenyl)-1,2-dimethyl-5-(quinox...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304872BDBM50304872(1,2-dimethyl-5-(quinoxalin-6-yl)-4-(thiophen-3-yl)...)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304852BDBM50304852(1,2-dimethyl-4-(3-(methylthio)phenyl)-5-(quinoxali...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304870BDBM50304870(4-(furan-3-yl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H...)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304862BDBM50304862(4-(3-fluorophenyl)-1,2-dimethyl-5-(quinoxalin-6-yl...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304839BDBM50304839(1,2-dimethyl-4-phenyl-5-(quinoxalin-6-yl)-1H-pyraz...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304854BDBM50304854(1,2-dimethyl-5-(quinoxalin-6-yl)-4-(3-(trifluorome...)
Affinity DataKi:  111nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304869BDBM50304869(4-(furan-2-yl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H...)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304864BDBM50304864(4-(3-bromophenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)...)
Affinity DataIC50: 220nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110208BDBM50110208(SB-431542 | cid_4521392 | 4-(5-(benzo[d][1,3]dioxo...)
Affinity DataIC50: 250nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304871BDBM50304871(1,2-dimethyl-5-(quinoxalin-6-yl)-4-(thiophen-2-yl)...)
Affinity DataKi:  365nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304856BDBM50304856(4-(3-(hydroxymethyl)phenyl)-1,2-dimethyl-5-(quinox...)
Affinity DataKi:  370nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304849BDBM50304849(4-(3-ethylphenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)...)
Affinity DataIC50: 390nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304859BDBM50304859(4-(3-acetylphenyl)-1,2-dimethyl-5-(quinoxalin-6-yl...)
Affinity DataKi:  410nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304861BDBM50304861(methyl 3-(1,2-dimethyl-3-oxo-5-(quinoxalin-6-yl)-2...)
Affinity DataKi:  440nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304850BDBM50304850(1,2-dimethyl-5-(quinoxalin-6-yl)-4-(3-vinylphenyl)...)
Affinity DataIC50: 560nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304873BDBM50304873(4-(benzo[c][1,2,5]oxadiazol-5-yl)-1,2-dimethyl-5-(...)
Affinity DataKi:  640nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304866BDBM50304866(N-(3-(1,2-dimethyl-3-oxo-5-(quinoxalin-6-yl)-2,3-d...)
Affinity DataKi:  920nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304862BDBM50304862(4-(3-fluorophenyl)-1,2-dimethyl-5-(quinoxalin-6-yl...)
Affinity DataIC50: 990nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304836BDBM50304836(1,2-dimethyl-4-(6-methylpyridin-2-yl)-5-(quinoxali...)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304854BDBM50304854(1,2-dimethyl-5-(quinoxalin-6-yl)-4-(3-(trifluorome...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304875BDBM50304875(4-(1H-indol-5-yl)-1,2-dimethyl-5-(quinoxalin-6-yl)...)
Affinity DataKi:  1.12E+3nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304853BDBM50304853(4-(3-methoxyphenyl)-1,2-dimethyl-5-(quinoxalin-6-y...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304835BDBM50304835(1,2-dimethyl-4-(pyridin-2-yl)-5-(quinoxalin-6-yl)-...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304874BDBM50304874(4-(benzo[b]thiophen-3-yl)-1,2-dimethyl-5-(quinoxal...)
Affinity DataKi:  1.87E+3nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304863BDBM50304863(4-(3-chlorophenyl)-1,2-dimethyl-5-(quinoxalin-6-yl...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304838BDBM50304838(1,2-dimethyl-4-(2-methylpyridin-4-yl)-5-(quinoxali...)
Affinity DataKi: >2.80E+3nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304837BDBM50304837(1,2-dimethyl-4-(pyridin-3-yl)-5-(quinoxalin-6-yl)-...)
Affinity DataKi: >2.80E+3nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304840BDBM50304840(1,2-dimethyl-5-(quinoxalin-6-yl)-4-m-tolyl-1H-pyra...)
Affinity DataIC50: 3.05E+3nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304855BDBM50304855(4-(3-(methoxymethyl)phenyl)-1,2-dimethyl-5-(quinox...)
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304858BDBM50304858(2-(3-(1,2-dimethyl-3-oxo-5-(quinoxalin-6-yl)-2,3-d...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304842BDBM50304842(4-(3-hydroxyphenyl)-1,2-dimethyl-5-(quinoxalin-6-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304852BDBM50304852(1,2-dimethyl-4-(3-(methylthio)phenyl)-5-(quinoxali...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304872BDBM50304872(1,2-dimethyl-5-(quinoxalin-6-yl)-4-(thiophen-3-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304841BDBM50304841(4-(2-hydroxyphenyl)-1,2-dimethyl-5-(quinoxalin-6-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304845BDBM50304845(4-(3-aminophenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304847BDBM50304847(2-(1,2-dimethyl-3-oxo-5-(quinoxalin-6-yl)-2,3-dihy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304865BDBM50304865(N-(3-(1,2-dimethyl-3-oxo-5-(quinoxalin-6-yl)-2,3-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304870BDBM50304870(4-(furan-3-yl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
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