Compile Data Set for Download or QSAR
Report error Found 86 Enz. Inhib. hit(s) with all data for entry = 50033334
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343508BDBM50343508(4-(4-(4-Fluorophenyl)-2-(methylthio)-1H-imidazol-5...)
Affinity DataIC50: 2nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343492BDBM50343492((S)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...)
Affinity DataIC50: 2nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343505BDBM50343505((S)-4-(4-(4-fluorophenyl)-2-(isopropylsulfinyl)-1H...)
Affinity DataIC50: 3nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343506BDBM50343506((R)-4-(4-(4-fluorophenyl)-2-(isopropylsulfinyl)-1H...)
Affinity DataIC50: 4nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343507BDBM50343507(4-(4-(4-Fluorophenyl)-2-(isopropylthio)-1H-imidazo...)
Affinity DataIC50: 4nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251985BDBM50251985(4-(4-(4-fluorophenyl)-2-(methylthio)-1H-imidazol-5...)
Affinity DataIC50: 5nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343505BDBM50343505((S)-4-(4-(4-fluorophenyl)-2-(isopropylsulfinyl)-1H...)
Affinity DataIC50: 6nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330167BDBM50330167(2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-(met...)
Affinity DataIC50: 9nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343504BDBM50343504((R)-N-cyclohexyl-4-(4-(4-fluorophenyl)-2-(isopropy...)
Affinity DataIC50: 11nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343502BDBM50343502((R)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...)
Affinity DataIC50: 11nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343493BDBM50343493((R)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...)
Affinity DataIC50: 12nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343487BDBM50343487((S)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...)
Affinity DataIC50: 12nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343489BDBM50343489(N-Cyclohexyl-4-(4-(4-fluorophenyl)-2-(isopropylthi...)
Affinity DataIC50: 12nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13336BDBM13336(4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...)
Affinity DataIC50: 15nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343485BDBM50343485(4-(4-(4-fluorophenyl)-2-((S)-methylsulfinyl)-1H-im...)
Affinity DataIC50: 17nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343488BDBM50343488(rac-N-Cyclohexyl-4-(4-(4-fluorophenyl)-2-(isopropy...)
Affinity DataIC50: 18nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343486BDBM50343486(4-(4-(4-fluorophenyl)-2-((R)-methylsulfinyl)-1H-im...)
Affinity DataIC50: 19nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343503BDBM50343503((S)-N-cyclohexyl-4-(4-(4-fluorophenyl)-2-(isopropy...)
Affinity DataIC50: 21nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343492BDBM50343492((S)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...)
Affinity DataIC50: 24nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343479BDBM50343479(4-(4-(4-fluorophenyl)-2-((R)-methylsulfinyl)-1H-im...)
Affinity DataIC50: 25nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343501BDBM50343501(4-(4-(4-Fluorophenyl)-2-(methylthio)-1H-imidazol-5...)
Affinity DataIC50: 26nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251974BDBM50251974(Cyclohexyl-{4-[4-(4-fluoro-phenyl)-2-methylsulfany...)
Affinity DataIC50: 27nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343485BDBM50343485(4-(4-(4-fluorophenyl)-2-((S)-methylsulfinyl)-1H-im...)
Affinity DataIC50: 27nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343491BDBM50343491((R)-N-cyclohexyl-4-(4-(4-fluorophenyl)-2-(methylsu...)
Affinity DataIC50: 29nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343483BDBM50343483(4-(4-(4-fluorophenyl)-2-((R)-methylsulfinyl)-1H-im...)
Affinity DataIC50: 31nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343490BDBM50343490((S)-N-cyclohexyl-4-(4-(4-fluorophenyl)-2-(methylsu...)
Affinity DataIC50: 34nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343487BDBM50343487((S)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...)
Affinity DataIC50: 34nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343482BDBM50343482(4-(4-(4-fluorophenyl)-2-((S)-methylsulfinyl)-1H-im...)
Affinity DataIC50: 36nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343498BDBM50343498(N-(4-(4-(4-Fluorophenyl)-2-(methylthio)-1H-imidazo...)
Affinity DataIC50: 37nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343484BDBM50343484(4-(4-(4-Fluorophenyl)-2-(methylthio)-1H-imidazol-5...)
Affinity DataIC50: 40nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343478BDBM50343478(4-(4-(4-fluorophenyl)-2-((S)-methylsulfinyl)-1H-im...)
Affinity DataIC50: 45nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343490BDBM50343490((S)-N-cyclohexyl-4-(4-(4-fluorophenyl)-2-(methylsu...)
Affinity DataIC50: 50nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130656BDBM50130656({4-[5-(4-Fluoro-phenyl)-2-methylsulfanyl-3H-imidaz...)
Affinity DataIC50: 50nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343501BDBM50343501(4-(4-(4-Fluorophenyl)-2-(methylthio)-1H-imidazol-5...)
Affinity DataIC50: 50nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343482BDBM50343482(4-(4-(4-fluorophenyl)-2-((S)-methylsulfinyl)-1H-im...)
Affinity DataIC50: 61nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130657BDBM50130657({4-[5-(4-Fluoro-phenyl)-2-methylsulfanyl-3H-imidaz...)
Affinity DataIC50: 65nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343494BDBM50343494((S)-2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-...)
Affinity DataIC50: 69nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343495BDBM50343495((R)-2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-...)
Affinity DataIC50: 77nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343478BDBM50343478(4-(4-(4-fluorophenyl)-2-((S)-methylsulfinyl)-1H-im...)
Affinity DataIC50: 95nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343507BDBM50343507(4-(4-(4-Fluorophenyl)-2-(isopropylthio)-1H-imidazo...)
Affinity DataIC50: 120nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343508BDBM50343508(4-(4-(4-Fluorophenyl)-2-(methylthio)-1H-imidazol-5...)
Affinity DataIC50: 130nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343494BDBM50343494((S)-2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-...)
Affinity DataIC50: 141nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343485BDBM50343485(4-(4-(4-fluorophenyl)-2-((S)-methylsulfinyl)-1H-im...)
Affinity DataIC50: 150nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343497BDBM50343497((R)-N-(4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H...)
Affinity DataIC50: 161nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343481BDBM50343481(4-(4-(4-fluorophenyl)-2-((R)-methylsulfinyl)-1H-im...)
Affinity DataIC50: 168nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251974BDBM50251974(Cyclohexyl-{4-[4-(4-fluoro-phenyl)-2-methylsulfany...)
Affinity DataIC50: 170nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343484BDBM50343484(4-(4-(4-Fluorophenyl)-2-(methylthio)-1H-imidazol-5...)
Affinity DataIC50: 180nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251985BDBM50251985(4-(4-(4-fluorophenyl)-2-(methylthio)-1H-imidazol-5...)
Affinity DataIC50: 180nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130648BDBM50130648(N-{4-[5-(4-Fluoro-phenyl)-3-methyl-2-methylsulfany...)
Affinity DataIC50: 188nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343496BDBM50343496((S)-N-(4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H...)
Affinity DataIC50: 197nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
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