Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50033382
TargetNeprilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344193((S)-2-(1-((S)-1-carboxy-2-(5-phenyloxazol-2-yl)eth...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNeprilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344195((S)-2-(1-((S)-1-carboxy-2-(5-(4-chlorophenyl)oxazo...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNeprilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50085452(Sampatrilat | (S)-2-[((S)-6-Amino-2-methanesulfony...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeprilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344191((S)-2-(1-((S)-1-carboxy-2-(5-phenyloxazol-2-yl)eth...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNatriuretic peptides A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344187((S)-2-((S)-1-((S)-2-(biphenyl-4-yl)-1-carboxyethyl...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of atrial natriuretic peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNeprilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344197((S)-2-(1-((S)-1-carboxy-2-(3-phenyl-1,2,4-oxadiazo...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNatriuretic peptides A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50085452(Sampatrilat | (S)-2-[((S)-6-Amino-2-methanesulfony...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of atrial natriuretic peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNeprilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344192((S)-2-(1-((S)-1-carboxy-2-(4-phenyloxazol-2-yl)eth...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNeprilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344194((S)-2-(1-((S)-1-carboxy-2-(4-methyl-5-phenyloxazol...)
Affinity DataIC50: 5nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNeprilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344196((S)-2-(1-((S)-1-carboxy-2-(5-phenyl-1,3,4-oxadiazo...)
Affinity DataIC50: 6nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNeprilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344190((S)-2-(1-((S)-1-carboxy-2-(4-phenyloxazol-2-yl)eth...)
Affinity DataIC50: 7nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNeprilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50281657(cis-4-[({1-[(2S)-2-carboxy-3-(2-methoxyethoxy)prop...)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNeprilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344189((S)-2-(1-((S)-1-carboxy-2-(4-isobutyloxazol-2-yl)e...)
Affinity DataIC50: 20nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNeprilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344188((S)-2-(1-((S)-1-carboxy-2-(4-ethyloxazol-2-yl)ethy...)
Affinity DataIC50: 22nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNatriuretic peptides A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344190((S)-2-(1-((S)-1-carboxy-2-(4-phenyloxazol-2-yl)eth...)
Affinity DataIC50: 25nMAssay Description:Inhibition of atrial natriuretic peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNeprilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344187((S)-2-((S)-1-((S)-2-(biphenyl-4-yl)-1-carboxyethyl...)
Affinity DataIC50: 28nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNatriuretic peptides A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344197((S)-2-(1-((S)-1-carboxy-2-(3-phenyl-1,2,4-oxadiazo...)
Affinity DataIC50: 58nMAssay Description:Inhibition of atrial natriuretic peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNatriuretic peptides A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344189((S)-2-(1-((S)-1-carboxy-2-(4-isobutyloxazol-2-yl)e...)
Affinity DataIC50: 75nMAssay Description:Inhibition of atrial natriuretic peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNatriuretic peptides A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344191((S)-2-(1-((S)-1-carboxy-2-(5-phenyloxazol-2-yl)eth...)
Affinity DataIC50: 82nMAssay Description:Inhibition of atrial natriuretic peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNatriuretic peptides A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344188((S)-2-(1-((S)-1-carboxy-2-(4-ethyloxazol-2-yl)ethy...)
Affinity DataIC50: 130nMAssay Description:Inhibition of atrial natriuretic peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNatriuretic peptides A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344192((S)-2-(1-((S)-1-carboxy-2-(4-phenyloxazol-2-yl)eth...)
Affinity DataIC50: 130nMAssay Description:Inhibition of atrial natriuretic peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNatriuretic peptides A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344195((S)-2-(1-((S)-1-carboxy-2-(5-(4-chlorophenyl)oxazo...)
Affinity DataIC50: 195nMAssay Description:Inhibition of atrial natriuretic peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNatriuretic peptides A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344194((S)-2-(1-((S)-1-carboxy-2-(4-methyl-5-phenyloxazol...)
Affinity DataIC50: 210nMAssay Description:Inhibition of atrial natriuretic peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNatriuretic peptides A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344193((S)-2-(1-((S)-1-carboxy-2-(5-phenyloxazol-2-yl)eth...)
Affinity DataIC50: 270nMAssay Description:Inhibition of atrial natriuretic peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNatriuretic peptides A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50344196((S)-2-(1-((S)-1-carboxy-2-(5-phenyl-1,3,4-oxadiazo...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of atrial natriuretic peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed