Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50033986
TargetCystine/glutamate transporter(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50053588BDBM50053588(4-((S)-Amino-carboxy-methyl)-benzoic acid | CHEMBL...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355002BDBM50355002(CHEMBL1834954)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097125BDBM50097125(Salazosulfapyridine | 2-Hydroxy-5-((4-((2-pyridiny...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355004BDBM50355004(CHEMBL1834956)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355009BDBM50355009(CHEMBL1614646)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355007BDBM50355007(CHEMBL1834959)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355011BDBM50355011(CHEMBL1834962)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355010BDBM50355010(CHEMBL1834961)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355012BDBM50355012(CHEMBL1834963)
Affinity DataIC50: 2.70E+5nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355006BDBM50355006(CHEMBL1834958)
Affinity DataIC50: 7.00E+5nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355003BDBM50355003(CHEMBL1834955)
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355008BDBM50355008(CHEMBL1834960)
Affinity DataIC50: 9.20E+5nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355005BDBM50355005(CHEMBL1834957)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355001BDBM50355001(CHEMBL1834953)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82251BDBM82251((S)-4CPG | CAS_134052-68-9 | (R)-4-Carboxyphenylgl...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60918BDBM60918(5-Amino-2-hydroxy-benzoic acid | cid_4075 | MLS001...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCystine/glutamate transporter(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 39340BDBM39340(MLS000069725 | cid_5336 | SMR000058213 | SULFAPYRI...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed