Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50004672
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370885BDBM50370885(CHEMBL375243)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485462BDBM50485462(CHEMBL313113)
Affinity DataIC50: 32nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075373BDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 33nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485455BDBM50485455(CHEMBL2059236)
Affinity DataIC50: 50nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134980BDBM50134980(1-(2-(2-hydroxy-3-(4-hydroxy-4-phenylpiperidin-1-y...)
Affinity DataIC50: 58nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420186BDBM50420186(ZOSUQUIDAR | ZOSUQUIDAR TRIHYDROCHLORIDE)
Affinity DataIC50: 59nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206310BDBM50206310(ELACRIDAR HYDROCHLORIDE | N-4-[2-(1,2,3,4-Tetrahyd...)
Affinity DataIC50: 72nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485461BDBM50485461(CHEMBL2058782)
Affinity DataIC50: 80nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022815BDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50: 102nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134979BDBM50134979((2-(3-(4-(4-fluorophenyl)piperazin-1-yl)-2-hydroxy...)
Affinity DataIC50: 150nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485460BDBM50485460(CHEMBL2058783)
Affinity DataIC50: 170nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485454BDBM50485454(CHEMBL2059231)
Affinity DataIC50: 200nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134994BDBM50134994((2-(2-hydroxy-3-(4-hydroxy-4-phenylpiperidin-1-yl)...)
Affinity DataIC50: 310nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067133BDBM50067133(CHEMBL631 | 1-[2-(2-Hydroxy-3-propylamino-propoxy)...)
Affinity DataIC50: 331nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485449BDBM50485449(CHEMBL2059235)
Affinity DataIC50: 380nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485465BDBM50485465(CHEMBL2059234)
Affinity DataIC50: 480nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485464BDBM50485464(CHEMBL2059232)
Affinity DataIC50: 500nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50390978BDBM50390978(VALSPODAR)
Affinity DataIC50: 501nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81939BDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataIC50: 575nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485450BDBM50485450(CHEMBL2058785)
Affinity DataIC50: 580nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135012BDBM50135012(1-[2-(2-Hydroxy-3-piperidin-1-yl-propoxy)-phenyl]-...)
Affinity DataIC50: 603nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485456BDBM50485456(CHEMBL2058784)
Affinity DataIC50: 650nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453799BDBM50453799(Niguldipine)
Affinity DataIC50: 708nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485457BDBM50485457(CHEMBL2058786)
Affinity DataIC50: 970nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485459BDBM50485459(CHEMBL2059229)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485463BDBM50485463(CHEMBL2059233)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485452BDBM50485452(CHEMBL1895098)
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485451BDBM50485451(CHEMBL2059230)
Affinity DataIC50: 3.55E+3nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 96113BDBM96113(cid_2951338 | [4-(3-morpholin-4-yl-2-oxidanyl-prop...)
Affinity DataIC50: 5.32E+3nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485458BDBM50485458(CHEMBL2059399)
Affinity DataIC50: 9.48E+3nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Vienna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485453BDBM50485453(CHEMBL2057229)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed