Found 13 Enz. Inhib. hit(s) with all data for entry = 50045906 
Affinity DataKi: 4.60E+3nMAssay Description:Competitive reversible inhibition of CYP2B6 in human liver microsomes incubated for 3 mins prior to NADPH addition measured after 10 mins by Dixon pl...More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+4nMAssay Description:Competitive inhibition of recombinant CYP3A4 (unknown origin) incubated for 3 mins prior to NADPH addition measured after 3 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of CYP2B6 in human liver microsomes incubated for 3 mins prior to NADPH addition measured after 10 mins by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of recombinant CYP2B6 (unknown origin) incubated for 3 mins prior to NADPH addition measured after 10 mins by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) incubated for 3 mins prior to NADPH addition measured after 3 mins by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes incubated for 3 mins prior to NADPH addition measured after 3 mins by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibition of CYP2B6 in human liver microsomes incubated for 3 mins prior to NADPH addition measured after 10 mins by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) incubated for 3 mins prior to NADPH addition measured after 3 mins by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibition of recombinant CYP2B6 (unknown origin) incubated for 3 mins prior to NADPH addition measured after 10 mins by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.25E+5nMAssay Description:Inhibition of CYP3A4 in human liver microsomes incubated for 3 mins prior to NADPH addition measured after 3 mins by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 5.90E+3nMAssay Description:Induction of CYP3A4 in human hepatocytes after 72 hrs relative to vehicle-treated controlMore data for this Ligand-Target Pair
Affinity DataEC50: 600nMAssay Description:Induction of CYP2B6 in human hepatocytes after 72 hrs relative to vehicle-treated controlMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
University Of Washington
Curated by ChEMBL
University Of Washington
Curated by ChEMBL
Affinity DataEC50: 3.00E+4nMAssay Description:Activation of human PXR expressed in human LS174T cellsMore data for this Ligand-Target Pair
