Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50040781
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400058BDBM50400058(CHEMBL2177749)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400072BDBM50400072(CHEMBL2178396 | US11191732, Example 3)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 108460BDBM108460(CHEMBL2178393 | US8604016, 17 | US9938267, Cmpd ID...)
Affinity DataKi:  2.00E+3nMAssay Description:Uncompetitive inhibition of human kidney glutaminase (124 to 669) assessed as reduction of glutamine hydrolysis by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400067BDBM50400067(CHEMBL2177740)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 108460BDBM108460(CHEMBL2178393 | US8604016, 17 | US9938267, Cmpd ID...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400050BDBM50400050(CHEMBL2177757 | US8604016, 1 | US9938267, Cmpd ID ...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400059BDBM50400059(CHEMBL2177748)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400068BDBM50400068(CHEMBL2177739)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400063BDBM50400063(CHEMBL2177744 | US11191732, Example 4)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400054BDBM50400054(CHEMBL2177753)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase liver isoform, mitochondrial(Mouse)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 108460BDBM108460(CHEMBL2178393 | US8604016, 17 | US9938267, Cmpd ID...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of mouse GLS2 using glutamine as substrate by fluorescence-based GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400070BDBM50400070(CHEMBL2178398)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400061BDBM50400061(CHEMBL2177746)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400060BDBM50400060(CHEMBL2177747)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400055BDBM50400055(CHEMBL2177752)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400066BDBM50400066(CHEMBL2177741)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400073BDBM50400073(CHEMBL2178395)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400069BDBM50400069(CHEMBL2177738)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400056BDBM50400056(CHEMBL2177751)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400052BDBM50400052(CHEMBL2177755)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400074BDBM50400074(CHEMBL2178394)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400071BDBM50400071(CHEMBL2178397)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400057BDBM50400057(CHEMBL2177750)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400062BDBM50400062(CHEMBL2177745)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400064BDBM50400064(CHEMBL2177743)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400049BDBM50400049(CHEMBL2177758 | US11191732, Example 2)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400065BDBM50400065(CHEMBL2177742)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400051BDBM50400051(CHEMBL2177756)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50400053BDBM50400053(CHEMBL2177754)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed