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Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50044076
TargetAmiloride-sensitive amine oxidase [copper-containing](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50000999(CHEBI:81724 | DIMINAZENE)
Affinity DataKi:  13nMAssay Description:Mixed type inhibition of recombinant human DAO expressed in drosophila S2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAmiloride-sensitive amine oxidase [copper-containing](Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM45440(4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...)
Affinity DataKi:  290nMAssay Description:Mixed type inhibition of recombinant human DAO expressed in drosophila S2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetDiamine acetyltransferase 1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM45440(4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human SSAT using spermidine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiamine acetyltransferase 1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50000999(CHEBI:81724 | DIMINAZENE)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of human SSAT using spermidine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM45440(4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...)
Affinity DataIC50:  720nMpH: 7.6Assay Description:Antagonist activity at NR1/NR2A receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced cur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50001000(CHEBI:29133 | DEXTRORPHAN | US11535596, Compound D...)
Affinity DataIC50:  1.30E+3nMpH: 7.6Assay Description:Antagonist activity at NR1/NR2A receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced cur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50044140(2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone | ...)
Affinity DataIC50:  3.31E+3nMpH: 7.6Assay Description:Antagonist activity at NR1/NR2A receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced cur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50062599(3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | EN3...)
Affinity DataIC50:  4.36E+3nMpH: 7.6Assay Description:Antagonist activity at NR1/NR2A receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced cur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)