Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 50044874
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50439637(CHEMBL2419601)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of human recombinant ACC2 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034496(CHEMBL3359261)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant ACC2 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034494(CHEMBL3359264)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant ACC2 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034371(CHEMBL3359265)
Affinity DataIC50:  24nMAssay Description:Inhibition of rat recombinant ACC1 assessed as incorporation of [14C]bicarbonate into [14C]malonyl-CoA by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034371(CHEMBL3359265)
Affinity DataIC50:  27nMAssay Description:Inhibition of human recombinant ACC1 assessed as incorporation of [14C]bicarbonate into [14C]malonyl-CoA by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034495(CHEMBL3359262)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant ACC2 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034371(CHEMBL3359265)
Affinity DataIC50:  33nMAssay Description:Inhibition of human recombinant ACC2 assessed as incorporation of [14C]bicarbonate into [14C]malonyl-CoA by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034496(CHEMBL3359261)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant ACC1 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034494(CHEMBL3359264)
Affinity DataIC50:  41nMAssay Description:Inhibition of human recombinant ACC1 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034371(CHEMBL3359265)
Affinity DataIC50:  45nMAssay Description:Inhibition of human recombinant ACC2 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034495(CHEMBL3359262)
Affinity DataIC50:  62nMAssay Description:Inhibition of human recombinant ACC1 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034499(CHEMBL3359259)
Affinity DataIC50:  78nMAssay Description:Inhibition of human recombinant ACC2 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034499(CHEMBL3359259)
Affinity DataIC50:  78nMAssay Description:Inhibition of human recombinant ACC2 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034371(CHEMBL3359265)
Affinity DataIC50:  98nMAssay Description:Inhibition of human recombinant ACC1 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50439637(CHEMBL2419601)
Affinity DataIC50:  111nMAssay Description:Inhibition of human recombinant ACC1 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034497(CHEMBL3359263)
Affinity DataIC50:  161nMAssay Description:Inhibition of human recombinant ACC2 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034497(CHEMBL3359263)
Affinity DataIC50:  317nMAssay Description:Inhibition of human recombinant ACC1 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034499(CHEMBL3359259)
Affinity DataIC50:  674nMAssay Description:Inhibition of human recombinant ACC1 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034499(CHEMBL3359259)
Affinity DataIC50:  676nMAssay Description:Inhibition of human recombinant ACC1 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034498(CHEMBL3359260)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant ACC2 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034498(CHEMBL3359260)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human recombinant ACC1 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034496(CHEMBL3359261)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of human ERG channel by patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034495(CHEMBL3359262)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human ERG channel by patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034494(CHEMBL3359264)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of human ERG channel by patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50439637(CHEMBL2419601)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of human ERG channel by patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034371(CHEMBL3359265)
Affinity DataIC50:  1.41E+5nMAssay Description:Inhibition of human ERG channel by patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed