Compile Data Set for Download or QSAR
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Found 18 Enz. Inhib. hit(s) with all data for entry = 50000414
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50343500((R)-N-(4-(4-(4-fluorophenyl)-1-methyl-2-(methylsul...)
Affinity DataIC50:  129nMAssay Description:Inhibition of p38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50:  500nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) by beta-galactosidase enzyme complementation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249599(CHEMBL4075428)
Affinity DataIC50:  700nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50:  710nMAssay Description:Inhibition of human PDE4D3 expressed in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249599(CHEMBL4075428)
Affinity DataIC50:  710nMAssay Description:Inhibition of P38 MAPKalpha in LPS-stimulated human whole blood assessed as decrease in TNFalpha levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50:  800nMAssay Description:Inhibition of P38 MAPKalpha in LPS-stimulated human whole blood assessed as decrease in TNFalpha levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human PDE4D2 expressed in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human PDE4B1 expressed in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249599(CHEMBL4075428)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human PDE4D2 expressed in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50238154(CHEMBL321494)
Affinity DataIC50:  2.76E+3nMAssay Description:Inhibition of human PDE4D3 expressed in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human PDE4A4 expressed in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249599(CHEMBL4075428)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human PDE4B1 expressed in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of human PDE4C1 expressed in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249599(CHEMBL4075428)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibition of human PDE4A4 expressed in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249599(CHEMBL4075428)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDE4C1 expressed in sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50130648(CHEMBL432798 | N-{4-[5-(4-Fluoro-phenyl)-3-methyl-...)
Affinity DataIC50:  2.86E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249599(CHEMBL4075428)
Affinity DataIC50:  8.30E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50:  2.13E+5nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed