TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of PCSK9 binding to LDLR in human HuH7 cells after 5 hrs by On-cell Western assayMore data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of recombinant human C-terminal His8-tagged PCSK9 expressed in Chinese hamster ovary cells by TR-FRET assayMore data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of binding of full-length recombinant human PCSK9 (M1 to Q692 residues) expressed in HEK293 cells to full-length LDLR (A1 to A699 residues...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKd: 700nMAssay Description:Binding affinity to recombinant human C-terminal His8-tagged PCSK9 expressed in Chinese hamster ovary cells by biolayer interferometryMore data for this Ligand-Target Pair