Compile Data Set for Download or QSAR
Report error Found 210 Enz. Inhib. hit(s) with all data for entry = 50001198
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271750BDBM50271750(CHEMBL4126095)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271775BDBM50271775(CHEMBL4129590)
Affinity DataIC50: 2nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271748BDBM50271748(CHEMBL4128577)
Affinity DataIC50: 2nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271747BDBM50271747(CHEMBL4127245)
Affinity DataIC50: 4nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271734BDBM50271734(CHEMBL4128540)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271780BDBM50271780(CHEMBL4126511)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271738BDBM50271738(CHEMBL4129219)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296011BDBM50296011(2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin...)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271728BDBM50271728(CHEMBL4127977)
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271751BDBM50271751(CHEMBL4127140)
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271774BDBM50271774(CHEMBL4128459)
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271752BDBM50271752(CHEMBL4128114)
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50271756BDBM50271756(CHEMBL4127319)
Affinity DataIC50: 13nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271744BDBM50271744(CHEMBL4128939)
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271739BDBM50271739(CHEMBL4126740)
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271729BDBM50271729(CHEMBL4128717)
Affinity DataIC50: 16nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271788BDBM50271788(CHEMBL4127064)
Affinity DataIC50: 16nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271740BDBM50271740(CHEMBL4127330)
Affinity DataIC50: 16nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271741BDBM50271741(CHEMBL4129791)
Affinity DataIC50: 20nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271755BDBM50271755(CHEMBL4129843)
Affinity DataIC50: 20nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296009BDBM50296009(2-ethyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)...)
Affinity DataIC50: 20nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271777BDBM50271777(CHEMBL4129362)
Affinity DataIC50: 20nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271776BDBM50271776(CHEMBL4125907)
Affinity DataIC50: 25nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271745BDBM50271745(CHEMBL4126566)
Affinity DataIC50: 25nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296010BDBM50296010(2-isobutyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271778BDBM50271778(CHEMBL4130310)
Affinity DataIC50: 25nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271789BDBM50271789(CHEMBL4125686)
Affinity DataIC50: 32nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271740BDBM50271740(CHEMBL4127330)
Affinity DataIC50: 32nMAssay Description:Inhibition of CAMKK2 in mouse N39 cells assessed as decrease in AMPKalpha phosphorylation at T172 preincubated for 80 mins followed by inomycin addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271779BDBM50271779(CHEMBL4127479)
Affinity DataIC50: 32nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271730BDBM50271730(CHEMBL4125774)
Affinity DataIC50: 32nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271745BDBM50271745(CHEMBL4126566)
Affinity DataIC50: 32nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50271752BDBM50271752(CHEMBL4128114)
Affinity DataIC50: 32nMAssay Description:Inhibition of IKK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271793BDBM50271793(CHEMBL4128483)
Affinity DataIC50: 50nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271794BDBM50271794(CHEMBL4126272)
Affinity DataIC50: 50nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271752BDBM50271752(CHEMBL4128114)
Affinity DataIC50: 63nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271780BDBM50271780(CHEMBL4126511)
Affinity DataIC50: 63nMAssay Description:Inhibition of CAMKK2 in mouse N39 cells assessed as decrease in AMPKalpha phosphorylation at T172 preincubated for 80 mins followed by inomycin addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271776BDBM50271776(CHEMBL4125907)
Affinity DataIC50: 79nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50271776BDBM50271776(CHEMBL4125907)
Affinity DataIC50: 79nMAssay Description:Inhibition of IKK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50271751BDBM50271751(CHEMBL4127140)
Affinity DataIC50: 79nMAssay Description:Inhibition of IKK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50271730BDBM50271730(CHEMBL4125774)
Affinity DataIC50: 79nMAssay Description:Inhibition of IKK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50271744BDBM50271744(CHEMBL4128939)
Affinity DataIC50: 100nMAssay Description:Inhibition of IKK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271756BDBM50271756(CHEMBL4127319)
Affinity DataIC50: 100nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271797BDBM50271797(CHEMBL4130255)
Affinity DataIC50: 100nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271748BDBM50271748(CHEMBL4128577)
Affinity DataIC50: 100nMAssay Description:Inhibition of CAMKK2 in mouse N39 cells assessed as decrease in AMPKalpha phosphorylation at T172 preincubated for 80 mins followed by inomycin addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50271745BDBM50271745(CHEMBL4126566)
Affinity DataIC50: 100nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50271778BDBM50271778(CHEMBL4130310)
Affinity DataIC50: 126nMAssay Description:Inhibition of IKK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50271750BDBM50271750(CHEMBL4126095)
Affinity DataIC50: 126nMAssay Description:Inhibition of IKK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271730BDBM50271730(CHEMBL4125774)
Affinity DataIC50: 126nMAssay Description:Inhibition of CAMKK2 in mouse N39 cells assessed as decrease in AMPKalpha phosphorylation at T172 preincubated for 80 mins followed by inomycin addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271792BDBM50271792(CHEMBL546682 | TCMDC-136271)
Affinity DataIC50: 126nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271751BDBM50271751(CHEMBL4127140)
Affinity DataIC50: 126nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
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