Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50018624
TargetCyclin-dependent kinase 8(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM50163795(CHEMBL3798382)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 8(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM50154944(CHEMBL3775535)
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 6nMAssay Description:Inhibition of RAF1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM50154943(CHEMBL3775576)
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM50610457(CHEMBL5281052)
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM50248631(CHEMBL4080906)
Affinity DataIC50: 12nMAssay Description:Inhibition of CDK8/Cyclin C (unknown origin) using RBER-IRStide as substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 8(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM50610458(CHEMBL5271114)
Affinity DataIC50: 14nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM50322535(3-[2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-meth...)
Affinity DataIC50: 14nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM21079(1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...)
Affinity DataIC50: 14nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 15nMAssay Description:Inhibition of FLK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 8(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM50610459(CHEMBL5270493)
Affinity DataIC50: 15nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 22nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 8(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM50610461(CHEMBL5270079)
Affinity DataKd:  30nMAssay Description:Binding affinity to CDK8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 30nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 58nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 90nMAssay Description:Inhibition of VEGFR-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM50610459(CHEMBL5270493)
Affinity DataIC50: 110nMAssay Description:Inhibition of HSP90 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM50248629(CHEMBL4076837 | US11471446, Compound DBA-9)
Affinity DataKd:  140nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM50459994(CHEMBL4226806 | US11471446, Compound DBA-8)
Affinity DataIC50: 640nMAssay Description:Inhibition of CDK8/Cyclin C (unknown origin) using RBER-IRStide as substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM50610462(CHEMBL5273868)
Affinity DataIC50: 740nMAssay Description:Inhibition of CDK8/Cyclin C (unknown origin) using RBER-IRStide as substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM50610460(CHEMBL5279965)
Affinity DataKd:  3.24E+3nMAssay Description:Binding affinity to CDK8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM50257749(6-bromo-N-propylquinazolin-4-amine | CHEMBL449571)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of CDK8/Cyclin C (unknown origin) using RBER-IRStide as substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM50154943(CHEMBL3775576)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HSP90 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Hefei Technology College

Curated by ChEMBL
LigandPNGBDBM50154944(CHEMBL3775535)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HSP90 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed