Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 9112
TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

LigandChemical structure of BindingDB Monomer ID 423466BDBM423466(WO2006061714-ID-11 | WO2006061714, P39.1 | cmdc.20...)
Affinity DataKi:  8.30nM IC50: 8.5nMAssay Description:The assays were carried out with 20 nM enzyme (except for MPI3, for which 10 nM enzyme was used) and 10 μM substrate at 37oC with continuous sha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

LigandChemical structure of BindingDB Monomer ID 442754BDBM442754(MPI4)
Affinity DataKi:  15nM IC50: 15nMAssay Description:The assays were carried out with 20 nM enzyme (except for MPI3, for which 10 nM enzyme was used) and 10 μM substrate at 37oC with continuous sha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

LigandChemical structure of BindingDB Monomer ID 420296BDBM420296(med.21724, Compound 61 | peptidomimetic aldehydes ...)
Affinity DataKi:  30nM IC50: 31nMAssay Description:The assays were carried out with 20 nM enzyme (except for MPI3, for which 10 nM enzyme was used) and 10 μM substrate at 37oC with continuous sha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

LigandChemical structure of BindingDB Monomer ID 419133BDBM419133(GC376 | BDBM429386 | US12180156, BS of GC373)
Affinity DataKi:  30nM IC50: 31nMAssay Description:The assays were carried out with 20 nM enzyme (except for MPI3, for which 10 nM enzyme was used) and 10 μM substrate at 37oC with continuous sha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

LigandChemical structure of BindingDB Monomer ID 442755BDBM442755(MPI5)
Affinity DataKi:  32nM IC50: 33nMAssay Description:The assays were carried out with 20 nM enzyme (except for MPI3, for which 10 nM enzyme was used) and 10 μM substrate at 37oC with continuous sha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

LigandChemical structure of BindingDB Monomer ID 442792BDBM442792(MPI7)
Affinity DataKi:  46nM IC50: 47nMAssay Description:The assays were carried out with 20 nM enzyme (except for MPI3, for which 10 nM enzyme was used) and 10 μM substrate at 37oC with continuous sha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

LigandChemical structure of BindingDB Monomer ID 442794BDBM442794(MPI9)
Affinity DataKi:  55nM IC50: 56nMAssay Description:The assays were carried out with 20 nM enzyme (except for MPI3, for which 10 nM enzyme was used) and 10 μM substrate at 37oC with continuous sha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

LigandChemical structure of BindingDB Monomer ID 442762BDBM442762(MPI6)
Affinity DataKi:  59nM IC50: 60nMAssay Description:The assays were carried out with 20 nM enzyme (except for MPI3, for which 10 nM enzyme was used) and 10 μM substrate at 37oC with continuous sha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

LigandChemical structure of BindingDB Monomer ID 442746BDBM442746(MPI1)
Affinity DataKi:  98nM IC50: 100nMAssay Description:The assays were carried out with 20 nM enzyme (except for MPI3, for which 10 nM enzyme was used) and 10 μM substrate at 37oC with continuous sha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

LigandChemical structure of BindingDB Monomer ID 429372BDBM429372(med.21724, Compound 43 | MPI2)
Affinity DataKi:  101nM IC50: 103nMAssay Description:The assays were carried out with 20 nM enzyme (except for MPI3, for which 10 nM enzyme was used) and 10 μM substrate at 37oC with continuous sha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

LigandChemical structure of BindingDB Monomer ID 429100BDBM429100(jm5b01461, Compound 45 | MPI8)
Affinity DataKi:  103nM IC50: 105nMAssay Description:The assays were carried out with 20 nM enzyme (except for MPI3, for which 10 nM enzyme was used) and 10 μM substrate at 37oC with continuous sha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details Article
PubMed