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Found 38 Enz. Inhib. hit(s) with all data for entry = 50016187
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593067(CHEMBL3408216)
Affinity DataIC50:  18nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50459995(CHEMBL4225966 | US11471446, Compound DBA-10)
Affinity DataIC50:  37nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593078(CHEMBL5188580)
Affinity DataIC50:  40nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593061(CHEMBL5183704)
Affinity DataIC50:  47nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593074(CHEMBL5199633)
Affinity DataIC50:  54nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593069(CHEMBL5193550)
Affinity DataIC50:  55nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593065(CHEMBL5186605)
Affinity DataIC50:  63nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593066(CHEMBL5203621)
Affinity DataIC50:  65nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593077(CHEMBL5187110)
Affinity DataIC50:  69nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593068(CHEMBL5169620)
Affinity DataIC50:  70nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  72nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593073(CHEMBL5200463)
Affinity DataIC50:  85nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593063(CHEMBL5199011)
Affinity DataIC50:  126nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593064(CHEMBL5187943)
Affinity DataIC50:  143nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593060(CHEMBL5179085)
Affinity DataIC50:  158nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593079(CHEMBL5205472)
Affinity DataIC50:  168nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593070(CHEMBL5192875)
Affinity DataIC50:  170nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593062(CHEMBL5169918)
Affinity DataIC50:  177nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593076(CHEMBL5200780)
Affinity DataIC50:  185nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593071(CHEMBL5177966)
Affinity DataIC50:  185nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593058(CHEMBL5170909)
Affinity DataIC50:  188nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593059(CHEMBL5175694)
Affinity DataIC50:  191nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593075(CHEMBL5202198)
Affinity DataIC50:  197nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593072(CHEMBL5207793)
Affinity DataIC50:  225nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593067(CHEMBL3408216)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593061(CHEMBL5183704)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593082(CHEMBL5182477)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593063(CHEMBL5199011)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593065(CHEMBL5186605)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593060(CHEMBL5179085)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593058(CHEMBL5170909)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593081(CHEMBL5204489)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593062(CHEMBL5169918)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593080(CHEMBL5175240)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593083(CHEMBL5200874)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50459995(CHEMBL4225966 | US11471446, Compound DBA-10)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593061(CHEMBL5183704)
Affinity DataEC50:  24nMAssay Description:Inhibition of CDK8 in human HCT-116 cells assessed as reduction in STAT1 phosphorylation at S727 residue measured after 24 hrs by Western blot assayMore data for this Ligand-Target Pair
In DepthDetails PubMed