Affinity DataIC50: 18nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 143nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 168nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 177nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 185nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 185nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 188nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 191nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 197nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 225nMAssay Description:Inhibition of CDK8 (unknown origin) incubated in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Affinity DataEC50: 24nMAssay Description:Inhibition of CDK8 in human HCT-116 cells assessed as reduction in STAT1 phosphorylation at S727 residue measured after 24 hrs by Western blot assayMore data for this Ligand-Target Pair